SCHEMBL1491148

SCHEMBL1491148

CCCCCCC(C)(C)c1nc(O)c(-c2cccc(C)c2)c(O)n1

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 15/20 0.48
CNR1 P21554 13/20 0.48
LTB4R Q15722 2/20 0.43
LTB4R2 Q9NPC1 2/20 0.43
TP53 P04637 1/20 0.43
TLR8 Q9NR97 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2112954 0.87 CNR2 (0.51) CNR2CNR1LTB4RLTB4R2TP53
SCHEMBL1192791 0.81 LTB4R (0.41) CNR2CNR1LTB4RLTB4R2TP53
SCHEMBL23602302 0.80 CNR2 (0.76) CNR2CNR1
SCHEMBL1433230 0.79 CNR2 (0.46) CNR2CNR1LTB4RLTB4R2
SCHEMBL1491145 0.73 CNR2 (0.46) CNR2CNR1LTB4RLTB4R2
SCHEMBL1491126 0.72 CNR2 (0.60) CNR2CNR1LTB4RLTB4R2TLR8
SCHEMBL1433257 0.72 CNR2 (0.39) CNR2CNR1LTB4RLTB4R2
SCHEMBL1433451 0.72 CNR2 (0.63) CNR2CNR1
SCHEMBL1238376 0.72 CNR1 (0.44) CNR2CNR1LTB4RLTB4R2
SCHEMBL13456051 0.70 CNR1 (0.40) CNR2CNR1LTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541431-B2 Pyrimidine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-09-24 US claimed
US-20120196900-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2012-08-02 US claimed
EP-2299819-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE The University of Tennessee Research Foundation (US) 2011-03-30 EP claimed
WO-2009143180-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION THE (US) 2009-11-26 WO claimed
US-20090286818-A1 Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2009-11-19 US claimed
US-20090286810-A1 Pyrimidine Non-Classical Cannabinoid Compounds and Related Methods of Use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2009-11-19 US claimed
US-8809373-B2 Pyridine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2014-08-19 US disclosed
US-8809373-B2 Pyridine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2014-08-19 US disclosed
US-8809373-B2 Pyridine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2014-08-19 US disclosed
US-8541431-B2 Pyrimidine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-09-24 US disclosed
US-8541431-B2 Pyrimidine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-09-24 US disclosed
US-8541431-B2 Pyrimidine non-classical cannabinoid compounds and related methods of use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-09-24 US disclosed
US-20130123304-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2013-05-16 US disclosed
WO-2009143180-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION THE (US) 2009-11-26 WO disclosed
US-20090286818-A1 Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2009-11-19 US disclosed
US-20090286818-A1 Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2009-11-19 US disclosed
US-20090286818-A1 Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2009-11-19 US disclosed
US-20090286810-A1 Pyrimidine Non-Classical Cannabinoid Compounds and Related Methods of Use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2009-11-19 US disclosed
US-20090286810-A1 Pyrimidine Non-Classical Cannabinoid Compounds and Related Methods of Use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2009-11-19 US disclosed
US-20090286810-A1 Pyrimidine Non-Classical Cannabinoid Compounds and Related Methods of Use THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286810-A1 Pyrimidine Non-Classical Cannabinoid Compounds and Related Methods of Use CNR1, CNR2, GPR18 CNR2 2/4885CNR1 1/4885LTB4R 230/4885
US-20130123304-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE CNR1, CNR2, NPY1R CNR2 2/4885CNR1 1/4885LTB4R 241/4885
US-20120196900-A1 PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE CNR1, CNR2, NPY1R CNR2 2/4885CNR1 1/4885LTB4R 241/4885
US-20090286818-A1 Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use CNR1, CNR2, NPY1R CNR2 2/4885CNR1 1/4885LTB4R 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.