Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 20/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 13/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12360000 | 1.00 | OPRD1 (0.57) | OPRD1OPRM1OPRK1 | |
| SCHEMBL72676 | 0.89 | OPRD1 (0.72) | OPRD1OPRM1OPRK1 | |
| SCHEMBL72381 | 0.89 | OPRD1 (0.72) | OPRD1OPRM1OPRK1 | |
| SCHEMBL72380 | 0.89 | OPRD1 (0.72) | OPRD1OPRM1OPRK1 | |
| SCHEMBL12359996 | 0.83 | OPRD1 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL12375391 | 0.82 | OPRD1 (0.59) | OPRD1OPRM1OPRK1 | |
| SCHEMBL12375392 | 0.82 | OPRD1 (0.59) | OPRD1OPRM1OPRK1 | |
| SCHEMBL1142697 | 0.81 | OPRD1 (0.56) | OPRD1OPRM1OPRK1 | |
| SCHEMBL14528036 | 0.78 | MEN1 (0.44) | OPRD1OPRM1 | |
| SCHEMBL12569769 | 0.78 | OPRD1 (0.60) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207745-A1 | SOLID FORMS OF 4--N,N-DIETHYLBENZAMIDE, COMPOSITIONS THEREOF, AND USES THEREWITH | ASTRAZENECA AB (SE) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207745-A1 | SOLID FORMS OF 4--N,N-DIETHYLBENZAMIDE, COMPOSITIONS THEREOF, AND USES THEREWITH | VHL, TPMT, NNMT | OPRD1 4300/4885OPRM1 3133/4885OPRK1 3060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.