Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 5/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13545305 | 0.87 | MMP12 (0.64) | TRPV1MMP12PKMPARP1ALDH1A1 | |
| SCHEMBL23432581 | 0.84 | KIF11 (0.54) | KIF11TRPV1MMP12PKMCYP11B1 | |
| SCHEMBL24508992 | 0.81 | KIF11 (0.54) | KIF11TRPV1MMP12PKMCYP11B1 | |
| SCHEMBL6297431 | 0.79 | KIF11 (0.62) | KIF11TRPV1MMP12PKMCYP11B1 | |
| SCHEMBL6297491 | 0.79 | KIF11 (0.58) | KIF11TRPV1PKMALDH1A1MAPT | |
| SCHEMBL24864966 | 0.79 | TRPV1 (0.65) | KIF11TRPV1MMP12PKMCYP11B1 | |
| SCHEMBL30336331 | 0.79 | TRPV1 (0.65) | KIF11TRPV1MMP12PKMCYP11B1 | |
| SCHEMBL280003 | 0.78 | MMP12 (0.75) | KIF11MMP12PKMCYP11B1CYP11B2 | |
| SCHEMBL10269414 | 0.78 | KIF11 (0.60) | KIF11TRPV1MMP12PKMCYP11B1 | |
| SCHEMBL4578101 | 0.78 | TRPV1 (0.56) | KIF11TRPV1PKMCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008326-B2 | 4-benzyledene-piperidin derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2011-08-30 | — | — | US | disclosed |
| US-8008326-B2 | 4-benzyledene-piperidin derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2011-08-30 | — | — | US | disclosed |
| US-20080312222-A1 | 4-Benzyledene-Piperidin Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-12-18 | — | — | US | disclosed |
| US-20080312222-A1 | 4-Benzyledene-Piperidin Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-12-18 | — | — | US | disclosed |
| CN-1133844-A | Osa-or thia-aliphatically bridged quinoxaline-2,3-diones | CIBA GEIGY AG (CH) | 1996-10-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312222-A1 | 4-Benzyledene-Piperidin Derivatives | GRIN2C, GRIN2A, GRIN1 | KIF11 4185/4885TRPV1 39/4885MMP12 3455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.