Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872527 | 0.77 | PRSS1 (0.31) | PRSS1CTSGCTRB1CMA1TDP1 | |
| SCHEMBL1289474 | 0.75 | — | — | |
| Formic Acid SCHEMBL29279052 | 0.71 | ELANE (0.34) | TDP1 | |
| SCHEMBL65267 | 0.67 | ELANE (0.40) | — | |
| SCHEMBL28872530 | 0.65 | ALDH1A1 (0.43) | TDP1 | |
| Ammonia Solution, Strong SCHEMBL25421893 | 0.65 | ELANE (0.39) | — | |
| SCHEMBL12855654 | 0.65 | ALDH1A1 (0.47) | — | |
| SCHEMBL7026388 | 0.65 | ELANE (0.39) | — | |
| SCHEMBL777024 | 0.63 | ALDH1A1 (0.32) | — | |
| SCHEMBL213629 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011017500-A1 | AMPHIPHILIC JANUS-DENDRIMERS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-02-10 | — | — | WO | disclosed |