Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 7/20 | 0.44 |
| ▸ | CCND1 | P24385 | 6/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183181 | 0.80 | PARP15 (0.50) | BRAFPARP15PARP10TNKS2PARP2 | |
| SCHEMBL30498863 | 0.80 | PARP15 (0.50) | BRAFPARP15PARP10TNKS2PARP2 | |
| SCHEMBL1659377 | 0.78 | TYMS (0.53) | TYMSCDK4CCND1ALDH1A1PARP1 | |
| SCHEMBL1658503 | 0.75 | ALDH1A1 (0.52) | TYMSCDK4CCND1ALDH1A1PARP1 | |
| SCHEMBL10625238 | 0.74 | KDM4E (0.69) | ALDH1A1 | |
| SCHEMBL3924921 | 0.72 | CHEK1 (0.59) | BRAFALDH1A1PARP1AURKAAURKB | |
| SCHEMBL8649896 | 0.72 | DAO (0.59) | BRAFPARP15PARP10TNKS2PARP2 | |
| SCHEMBL670670 | 0.70 | CYP1A2 (0.52) | CDK4CCND1ALDH1A1LMNA | |
| SCHEMBL1038250 | 0.69 | PARP1 (0.53) | TYMSCDK4CCND1PARP15ALDH1A1 | |
| SCHEMBL29379996 | 0.69 | PARP1 (0.53) | TYMSCDK4CCND1PARP15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152116-A1 | NANOASSAYS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-06-23 | — | — | US | disclosed |
| US-7919019-B2 | Nanostructure enhanced luminescent devices | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-04-05 | — | — | US | disclosed |
| US-7879575-B2 | Tubes, rods from nylon; kits | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-02-01 | — | — | US | disclosed |
| US-20090246888-A1 | NANOASSAYS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-10-01 | — | — | US | disclosed |
| US-20080286856-A1 | Nanostructure Enhanced Luminescent Devices | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080193956-A1 | Nanostructure Enhanced Luminescence | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-08-14 | — | — | US | disclosed |
| WO-2006116686-A2 | NANOSTRUCTURE ENHANCED LUMINESCENT DEVICES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-11-02 | — | — | WO | disclosed |
| WO-2006116687-A2 | NANOASSAYS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-11-02 | — | — | WO | disclosed |