Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24665385 | 0.82 | ALOX5 (0.52) | ALDH1A1ALOX5HPRT1TYMSTDP1 | |
| SCHEMBL31454054 | 0.79 | DAO (0.52) | ALDH1A1ALOX5HPRT1TYMSTDP1 | |
| SCHEMBL2325768 | 0.75 | PARP1 (0.47) | ALDH1A1HPRT1TYMSTDP1L3MBTL1 | |
| SCHEMBL1236330 | 0.75 | TYMS (0.50) | ALDH1A1TYMSPARP1LMNACDK4 | |
| SCHEMBL460847 | 0.75 | KDM4E (0.57) | ALDH1A1TYMSTDP1L3MBTL1PARP1 | |
| SCHEMBL1659377 | 0.75 | TYMS (0.53) | ALDH1A1TYMSPARP1RAB9ACDK4 | |
| SCHEMBL29766 | 0.74 | ALOX5 (0.70) | ALDH1A1ALOX5PARP1TSHRHSD17B10 | |
| SCHEMBL29349675 | 0.74 | ALOX5 (0.70) | ALDH1A1ALOX5PARP1TSHRHSD17B10 | |
| SCHEMBL7755100 | 0.73 | HPRT1 (0.55) | ALDH1A1HPRT1TYMSTDP1L3MBTL1 | |
| Charcoal, Activated SCHEMBL31491466 | 0.71 | ALOX5 (0.67) | ALDH1A1ALOX5PARP1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160216272-A1 | KIT AND METHOD FOR THE LABELLING OF BIOMOLECULES | CYANAGEN S R L (IT) | 2016-07-28 | — | — | US | claimed |
| EP-2314597-B1 | Kit and method for the labelling of biomolecules | CYANAGEN SRL (IT) | 2012-11-28 | — | — | EP | claimed |
| EP-2314597-A1 | Kit and method for the labelling of biomolecules | Cyanagen Srl (IT) | 2011-04-27 | — | — | EP | claimed |
| US-20110092676-A1 | KIT AND METHOD FOR THE LABELLING OF BIOMOLECULES | CYANAGEN S.R.L. (IT) | 2011-04-21 | — | — | US | claimed |
| US-20100048692-A1 | Naphthofuranone Derivatives as Specific Inhibitors of Thymidylate Synthases | TYDOCKPHARMA S.R.L. (IT) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092676-A1 | KIT AND METHOD FOR THE LABELLING OF BIOMOLECULES | KIT, UNG, ALKBH1 | ALDH1A1 385/4885ALOX5 4135/4885HPRT1 281/4885 |
| US-20100048692-A1 | Naphthofuranone Derivatives as Specific Inhibitors of Thymidylate Synthases | TYMS, TYMP, DNTT | ALDH1A1 1436/4885ALOX5 1356/4885HPRT1 290/4885 |
| US-20160216272-A1 | KIT AND METHOD FOR THE LABELLING OF BIOMOLECULES | KIT, UNG, ALKBH1 | ALDH1A1 385/4885ALOX5 4135/4885HPRT1 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.