Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.46 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12366411 | 0.89 | RXRA (0.41) | RXRANR1H2NR1H3GNRHR | |
| SCHEMBL12366310 | 0.88 | RXRA (0.59) | RXRANR1H2NR1H3GNRHRKDM4E | |
| SCHEMBL12366423 | 0.88 | RXRA (0.49) | RXRANR1H2NR1H3GNRHRKDM4E | |
| SCHEMBL12366440 | 0.88 | RXRA (0.43) | RXRANR1H2NR1H3GNRHRKDM4E | |
| SCHEMBL12366306 | 0.87 | RXRA (0.47) | RXRANR1H2NR1H3GNRHRKDM4E | |
| SCHEMBL12366392 | 0.86 | RXRA (0.45) | RXRANR1H2NR1H3GNRHRKDM4E | |
| SCHEMBL12366502 | 0.86 | RXRA (0.46) | RXRANR1H2NR1H3GNRHRKDM4E | |
| SCHEMBL12366272 | 0.85 | RXRA (0.42) | RXRANR1H2NR1H3GNRHRKDM4E | |
| SCHEMBL12366308 | 0.83 | RXRA (0.43) | RXRANR1H2NR1H3KDM4EALDH1A1 | |
| SCHEMBL12366212 | 0.82 | CNR1 (0.44) | RXRANR1H2NR1H3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |