Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.43 |
| ▸ | PDE8B | O95263 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2245664 | 0.83 | GPR119 (0.46) | GPR119PDE8BADRA1A | |
| Hydrochloric Acid SCHEMBL2248590 | 0.82 | GPR119 (0.43) | GPR119PDE8B | |
| SCHEMBL12367747 | 0.80 | GPR119 (0.42) | GPR119PDE8B | |
| SCHEMBL12409004 | 0.80 | GPR119 (0.50) | GPR119PDE8B | |
| SCHEMBL2248808 | 0.79 | GPR119 (0.48) | GPR119 | |
| SCHEMBL1103984 | 0.77 | GPR119 (0.48) | GPR119 | |
| SCHEMBL11957018 | 0.76 | GPR119 (0.46) | GPR119PDE8B | |
| SCHEMBL27855620 | 0.74 | AOC3 (0.51) | GPR119 | |
| SCHEMBL1103982 | 0.74 | MAPK8 (0.47) | GPR119PDE8B | |
| SCHEMBL17712603 | 0.74 | GPR119 (0.49) | GPR119PDE8B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190263-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190263-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR65, GPR39 | GPR119 1/4885PDE8B 1181/4885ADRA1A 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.