Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.61 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.58 |
| ▸ | CDK4 | P11802 | 4/20 | 0.55 |
| ▸ | CCND1 | P24385 | 4/20 | 0.55 |
| ▸ | CCND3 | P30281 | 2/20 | 0.55 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.54 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 4/20 | 0.53 |
| ▸ | CDK1 | P06493 | 3/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.48 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91469 | 0.87 | CTSK (0.49) | IKBKBHRH4CDK4CCND1MAPK8 | |
| SCHEMBL91478 | 0.83 | CTSK (0.58) | HRH4CDK4CCND1CCND3CDK6 | |
| SCHEMBL91484 | 0.82 | CTSK (0.60) | HRH4CDK4CCND1CCND3CDK6 | |
| SCHEMBL13779899 | 0.81 | IKBKB (0.57) | IKBKBHRH4CDK4CCND1CCND3 | |
| SCHEMBL91448 | 0.80 | IKBKB (0.52) | IKBKBHRH4CDK4CCND1CCND3 | |
| SCHEMBL13162840 | 0.80 | KDM4E (0.60) | IKBKBHRH4CDK4CCND1CCND3 | |
| SCHEMBL13779903 | 0.80 | HRH4 (0.80) | IKBKBHRH4CDK4CCND1MAPK8 | |
| SCHEMBL24065221 | 0.79 | CDK1 (0.54) | HRH4CDK4CCND1MAPK8MAPK9 | |
| SCHEMBL18677322 | 0.79 | CDK1 (0.54) | HRH4CDK4CCND1MAPK8MAPK9 | |
| SCHEMBL15830033 | 0.79 | MAPK1 (0.62) | HRH4MAPK8MAPK9MAPK10RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164612-A9 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2023164612-A1 | MODULATORS OF MYC FAMILY PROTO-ONCOGENE PROTEIN | NALO THERAPEUTICS (US) | 2023-08-31 | — | — | WO | disclosed |
| US-7998969-B2 | enzyme inhibitors such as 4-[2-(1-Benzyl-piperidin-4-ylamino)-pyrimidin-4-yloxy]-3,5-dimethyl-benzonitrile, used in combination with other viricides, for preventing and treatment of viral infections such as HIV, AIDS and AIDS related diseases | ROCHE PALO ALTO LLC (US) | 2011-08-16 | — | — | US | disclosed |
| US-20080146595-A1 | Non-nucleoside reverse transcriptase inhibitors | ROCHE PALO ALTO LLC | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146595-A1 | Non-nucleoside reverse transcriptase inhibitors | NQO2, SAMHD1, POLR2A | IKBKB 1774/4885HRH4 1845/4885CDK4 550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.