Androstenedione

Androstenedione

SCHEMBL12367193

C[C@]12CCC(=O)C=C1CC[C@@H]1C2CC[C@]2(C)C(=O)CCC12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 18/20 1.00
ALDH1A1 P00352 2/20 1.00
LMNA P02545 2/20 1.00
SHBG P04278 2/20 1.00
SERPINA6 P08185 2/20 1.00
MAPK1 P28482 2/20 1.00
HSD17B3 P37058 2/20 1.00
SNCA P37840 2/20 1.00
BLM P54132 2/20 1.00
PMP22 Q01453 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
NPSR1 Q6W5P4 2/20 1.00
HSD17B10 Q99714 2/20 1.00
TSHR P16473 1/20 1.00
SRD5A1 P18405 1/20 0.78
SRD5A2 P31213 1/20 0.78
OR51E2 Q9H255 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Androstenedione SCHEMBL27901 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL15963582 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL9310209 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL13752932 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL13753017 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL11876371 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL15369366 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL12153462 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL21265627 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL15963154 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023288123-A1 METHODS AND INTERMEDIATES FOR THE PREPARATION OF 3.ALPHA.,7.ALPHA.,11.BETA.-TRIHYDROXY-6.ALPHA.-ETHYL-5.BETA.-CHOLAN-24-OIC ACID INTERECEPT PHARMACEUTICALS, INC. (US) 2023-01-19 WO disclosed
EP-2449128-B1 Enzymatic process for the preparation of testosterone using a \"tag\ F I S - FABBRICA ITALIANA SINTETICI S P A (IT) 2017-05-10 EP disclosed
US-20110207172-A1 PROCESS FOR THE PREPARATION OF TESTOSTERONE F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) 2011-08-25 US disclosed
US-20110207172-A1 PROCESS FOR THE PREPARATION OF TESTOSTERONE F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) 2011-08-25 US disclosed
WO-2011000693-A1 PROCESS FOR THE PREPARATION OF TESTOSTERONE F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) 2011-01-06 WO disclosed
EP-2093285-A1 Method for biocatalysis using filamentous fungi The University of the West Indies (JM) 2009-08-26 EP disclosed
US-7238507-B2 Aspergillus ochraceus 11 alpha hydroxylase and oxidoreductase PHARMACIA CORPORATION (US) 2007-07-03 US disclosed
US-7238507-B2 Aspergillus ochraceus 11 alpha hydroxylase and oxidoreductase PHARMACIA CORPORATION (US) 2007-07-03 US disclosed