Androstenedione

Androstenedione

SCHEMBL27901

C[C@]12CCC(=O)C=C1CC[C@@H]1[C@H]2CC[C@]2(C)C(=O)CC[C@@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 18/20 1.00
ALDH1A1 P00352 2/20 1.00
LMNA P02545 2/20 1.00
SHBG P04278 2/20 1.00
SERPINA6 P08185 2/20 1.00
MAPK1 P28482 2/20 1.00
HSD17B3 P37058 2/20 1.00
SNCA P37840 2/20 1.00
BLM P54132 2/20 1.00
PMP22 Q01453 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
NPSR1 Q6W5P4 2/20 1.00
HSD17B10 Q99714 2/20 1.00
TSHR P16473 1/20 1.00
SRD5A1 P18405 1/20 0.78
SRD5A2 P31213 1/20 0.78
OR51E2 Q9H255 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Androstenedione SCHEMBL15963582 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL9310209 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL12367193 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL13752932 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL13753017 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL11876371 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL15369366 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL12153462 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL21265627 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL15963154 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078142-A1 FULLY-CONTINUOUS SYNTHESIS METHOD OF CYPROTERONE ACETATE UNIV FUDAN (CN) 2026-03-19 US claimed
US-12280021-B2 Affinity medicant conjugate AF CHEMICALS, LLC (US) 2025-04-22 US claimed
CN-119125361-A Rapid detection method for 27 steroid hormones in mangrove plants 中国科学院南海海洋研究所 2024-12-13 CN claimed
CN-117836004-A Application of ST lipoid compound in preparation of nucleic acid delivery reagent and related products 中国医学科学院基础医学研究所 2024-04-05 CN claimed
CN-114933624-B Artificial synthesis method of natural product (+) -digitonin 大连理工大学 2024-02-20 CN claimed
US-20230346800-A1 REDUCTION OF THE INCIDENCE OR RECURRENCE OF BREAST CANCER IN POSTMENOPAUSAL WOMEN TREATED WITH INTRAVAGINAL SEX STEROID PRECURSOR ENDORECHERCHE, INC. (CA) 2023-11-02 US claimed
US-11690852-B2 Reduction of the incidence or recurrence of breast cancer in postmenopausal women treated with intravaginal sex steroid precursor ENDORECHERCHE. INC. 2023-07-04 US claimed
CN-110656147-B Biological dehydrogenation method of androstenedione C1,2 position 湖南新合新生物医药有限公司 2023-05-05 CN claimed
CN-115747839-A Method for preparing 19-aldehyde-4-androstene-3,17-diketone by electrocatalytic oxidation of nickel-molybdenum oxide 浙江工业大学 2023-03-07 CN claimed
US-11578096-B2 Method for preparing 7alpha-methyl-19-aldehyde-4-androstene-3,17-dione by electrocatalytic oxidation ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2023-02-14 US claimed
EP-0072880-A1 A composition for use in the control of ovulation of female bovines COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1983-03-02 EP claimed
EP-0008214-B1 MICROORGANISMS AND THEIR USE IN PRODUCING ANDROST-4-ENE-3,17-DIONE THE UPJOHN COMPANY (US) 1982-06-02 EP claimed
US-4331657-A IMMUNIZING AGAINST A STEROIDAL ANDROGEN OR OESTROGEN COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1982-05-25 US claimed
US-4273872-A TRANSFORMATION OF CHOLESTEROL TO D-4-CHOLESTERN-3-ONE IN A PARAFFINIC HYDROCARBON MEDIA CONTAINING BACTERIA SNAMPROGETTI S.P.A. (IT) 1981-06-16 US claimed
US-4272445-A STEROIDS, BASIC CATALYSTS, ALKYLATION BEECHAM GROUP LIMITED (GB) 1981-06-09 US claimed
EP-0027829-A1 Process for the preparation of 9-alpha-hydroxy-4-androstene-3,17-dione SCHERING AKTIENGESELLSCHAFT (DE) 1981-05-06 EP claimed
US-4237220-A Process for preparing 9α-hydroxy-4-androstene-3,17-dione SCHERING, AKTIENGESELLSCHAFT (DE) 1980-12-02 US claimed
US-4100027-A Process for the preparation of 4-androstene-3,17-dione derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1978-07-11 US claimed
US-4100026-A Process for the preparation of 4-androstene-3,17-dione derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1978-07-11 US claimed
US-3966714-A Process for the preparation of a Δ4 -3-keto steroid 17-propiolactone SCHERING AKTIENGESELLSCHAFT (DT) 1976-06-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12280021-B2 Affinity medicant conjugate FCER2, HDGF, FCGR2A CYP19A1 972/4885ALDH1A1 3966/4885LMNA 3666/4885
US-20260078142-A1 FULLY-CONTINUOUS SYNTHESIS METHOD OF CYPROTERONE ACETATE CYP17A1, CYP21A2, HSD17B2 CYP19A1 14/4885ALDH1A1 241/4885LMNA 2995/4885
US-11578096-B2 Method for preparing 7alpha-methyl-19-aldehyde-4-androstene-3,17-dione by electrocatalytic oxidation HSD17B1, HSD17B2, HSD17B7 CYP19A1 18/4885ALDH1A1 74/4885LMNA 2299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.