Androstenedione

Androstenedione

SCHEMBL23272

C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 18/20 1.00
ALDH1A1 P00352 2/20 1.00
LMNA P02545 2/20 1.00
SHBG P04278 2/20 1.00
SERPINA6 P08185 2/20 1.00
MAPK1 P28482 2/20 1.00
HSD17B3 P37058 2/20 1.00
SNCA P37840 2/20 1.00
BLM P54132 2/20 1.00
PMP22 Q01453 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
NPSR1 Q6W5P4 2/20 1.00
HSD17B10 Q99714 2/20 1.00
TSHR P16473 1/20 1.00
SRD5A1 P18405 1/20 0.78
SRD5A2 P31213 1/20 0.78
OR51E2 Q9H255 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Androstenedione SCHEMBL27901 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL15963582 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL9310209 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL12367193 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL13752932 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL13753017 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL11876371 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL15369366 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL12153462 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL21265627 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17994 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146228-A1 COMPOSITIONS AND METHODS FOR INDUCING OOCYTE MATURATION GAMETO, INC. (US) 2026-05-28 US claimed
CN-115537446-B Application of rhodococcus aether in conversion of cholesterol to produce 4-androstenedione TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE (CN) 2026-05-26 CN claimed
CN-122080102-A Dehydrogenization epiandrosterone Process for the preparation of ketones 2026-05-26 CN claimed
CN-122081438-A Bencholecachol alcohol Process for the preparation of ketones 2026-05-26 CN claimed
US-20260140124-A1 PCOS STRATIFICATION THE UNIVERSITY OF BIRMINGHAM (GB) 2026-05-21 US claimed
EP-4740024-A1 ENDOMETRIOSIS MARKERS AND METHODS OF DIAGNOSING ENDOMETRIOSIS The University Court Of The University of Edinburgh (GB) 2026-05-13 EP claimed
CN-122017085-A Method for simultaneously detecting multiple steroid hormones in serum 北京大学第三医院(北京大学第三临床医学院) 2026-05-12 CN claimed
CN-122011076-A Preparation method of spirolactone 浙江神洲药业有限公司 2026-05-12 CN claimed
CN-122012425-A Steroid 11 alpha-hydroxylase and use thereof 沈阳博泰生物制药有限公司 2026-05-12 CN claimed
US-20260115204-A1 ENTHESIS HEALING UNIV UTAH RES FOUND (US) 2026-04-30 US claimed
US-4100027-A Process for the preparation of 4-androstene-3,17-dione derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1978-07-11 US claimed
US-4100026-A Process for the preparation of 4-androstene-3,17-dione derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1978-07-11 US claimed
US-4098647-A Composition of matter and process THE UPJOHN COMPANY (US) 1978-07-04 US claimed
US-4097335-A AEROBIC CULTIVATION OF MYCOBACTERIUM FORTIUTUM THE UPJOHN COMPANY (US) 1978-06-27 US claimed
US-4062729-A Microbial transformation of steroids THE UPJOHN COMPANY (US) 1977-12-13 US claimed
US-4057542-A Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone G. D. SEARLE & CO. (US) 1977-11-08 US claimed
US-4042459-A CULTIVATING A STEROID FROM MYCOBACTERIUM THE UPJOHN COMPANY (US) 1977-08-16 US claimed
US-4039381-A STEROIDS THE UPJOHN COMPANY (US) 1977-08-02 US claimed
US-3990956-A Electrochemical reduction of α,β-unsaturated keto steroids SCHERING AKTIENGESELLSCHAFT (DT) 1976-11-09 US claimed
US-3966714-A Process for the preparation of a Δ4 -3-keto steroid 17-propiolactone SCHERING AKTIENGESELLSCHAFT (DT) 1976-06-29 US claimed