Androstenedione

Androstenedione

SCHEMBL21265627

C[C@]12CCC(=O)C=C1CC[C@@H]1C2CC[C@]2(C)C(=O)CC[C@@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 18/20 1.00
ALDH1A1 P00352 2/20 1.00
LMNA P02545 2/20 1.00
SHBG P04278 2/20 1.00
SERPINA6 P08185 2/20 1.00
MAPK1 P28482 2/20 1.00
HSD17B3 P37058 2/20 1.00
SNCA P37840 2/20 1.00
BLM P54132 2/20 1.00
PMP22 Q01453 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
NPSR1 Q6W5P4 2/20 1.00
HSD17B10 Q99714 2/20 1.00
TSHR P16473 1/20 1.00
SRD5A1 P18405 1/20 0.78
SRD5A2 P31213 1/20 0.78
OR51E2 Q9H255 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Androstenedione SCHEMBL27901 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL15963582 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL9310209 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL12367193 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL13752932 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL13753017 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL11876371 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL15369366 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL12153462 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6
Androstenedione SCHEMBL15963154 1.00 CYP19A1 (1.00) CYP19A1ALDH1A1LMNASHBGSERPINA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051387-A1 STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) 2025-02-13 US disclosed
US-12139508-B2 Steroid derivative regulators, method for preparing the same, and uses thereof JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) 2024-11-12 US disclosed
CN-114805462-A Steroid derivative regulator and preparation method and application thereof 江苏豪森药业集团有限公司 2022-07-29 CN disclosed
CN-114656514-A Steroid derivative regulator and preparation method and application thereof 江苏豪森药业集团有限公司 2022-06-24 CN disclosed
US-20210139530-A1 STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) 2021-05-13 US disclosed
US-20210139530-A1 STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) 2021-05-13 US disclosed
EP-3750908-A1 STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) 2020-12-16 EP disclosed
EP-3750908-A1 STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) 2020-12-16 EP disclosed
CN-110709409-A Steroid derivative regulator and preparation method and application thereof 江苏豪森药业集团有限公司 2020-01-17 CN disclosed
WO-2019154257-A1 STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF 江苏豪森药业集团有限公司 2019-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12139508-B2 Steroid derivative regulators, method for preparing the same, and uses thereof GABRD, GABRR1, GABRA1 CYP19A1 56/4885ALDH1A1 959/4885LMNA 3740/4885
US-20250051387-A1 STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF GABRD, GABRR1, GABRA1 CYP19A1 56/4885ALDH1A1 959/4885LMNA 3740/4885
US-20210139530-A1 STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF GABRD, GABRR1, GABRA1 CYP19A1 56/4885ALDH1A1 959/4885LMNA 3740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.