Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1236716 | 0.78 | MAPT (0.41) | CNR1CNR2MAPTKDM4EHSD17B10 | |
| SCHEMBL28643746 | 0.77 | SIRT1 (0.67) | MAPTKDM4EHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL28054006 | 0.73 | CNR2 (0.76) | CNR1CNR2HSD17B10HPGDALDH1A1 | |
| SCHEMBL27906906 | 0.72 | MAPT (0.63) | MAPTKDM4EHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL1236488 | 0.70 | ALDH1A1 (0.50) | CNR1CNR2MAPTKDM4EHSD17B10 | |
| SCHEMBL30176966 | 0.69 | AR (0.59) | MAPTKDM4EHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL28380626 | 0.69 | AR (0.59) | MAPTKDM4EHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL13087454 | 0.68 | MAPT (0.50) | MAPTKDM4EHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL16375371 | 0.67 | CYP19A1 (0.63) | MAPTKDM4EHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL18409613 | 0.66 | SIRT1 (0.56) | MAPTKDM4EHSD17B10TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | claimed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | claimed |
| WO-2011022679-A2 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2011-02-24 | — | — | WO | claimed |
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| WO-2011022679-A2 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2011-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, GPR18 | CNR1 1/4885CNR2 2/4885MAPT 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.