Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1234944 | 0.85 | SIRT1 (0.36) | SIRT1CNR1CNR2ABL1EGFR | |
| SCHEMBL1236041 | 0.82 | CNR1 (0.33) | ALDH1A1SMN1; SMN2MEN1TP53MAPT | |
| SCHEMBL1236488 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2ALOX15MEN1TP53 | |
| SCHEMBL1235883 | 0.78 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2ALOX15MEN1TP53 | |
| SCHEMBL1236716 | 0.75 | MAPT (0.41) | ALDH1A1SMN1; SMN2ALOX15MEN1TP53 | |
| SCHEMBL1236224 | 0.72 | CNR1 (0.43) | ALDH1A1SMN1; SMN2ALOX15MEN1TP53 | |
| SCHEMBL1235919 | 0.71 | CNR2 (0.51) | CNR1CNR2 | |
| SCHEMBL1193258 | 0.71 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2MEN1KMT2ACNR1 | |
| SCHEMBL1236879 | 0.71 | CNR2 (0.63) | ALDH1A1SMN1; SMN2ALOX15MEN1TP53 | |
| SCHEMBL1236078 | 0.70 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2ALOX15MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | claimed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | claimed |
| WO-2011022679-A2 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2011-02-24 | — | — | WO | claimed |
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| WO-2011022679-A2 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2011-02-24 | — | — | WO | disclosed |
| WO-2011022679-A2 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2011-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, GPR18 | ALDH1A1 576/4885SMN1; SMN2 3537/4885ALOX15 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.