SCHEMBL12371008

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13267179	0.82	ALDH1A1 (0.55)	HTTSMN1; SMN2NPC1RAB9AALDH1A1
	SCHEMBL12371032	0.82	NOTUM (0.38)	SMN1; SMN2NPC1RAB9APOLB
	SCHEMBL12371020	0.81	NPC1 (0.43)	NPC1RAB9AALDH1A1HSD17B10HPGD
	SCHEMBL12371048	0.80	ALDH1A1 (0.44)	SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10
	SCHEMBL12371067	0.78	KDM4E (0.40)	HTTRAB9AALDH1A1HSD17B10HPGD
	SCHEMBL12371000	0.78	MAP1LC3B (0.40)	SMN1; SMN2ALDH1A1HPGDATMMEN1
	SCHEMBL9628155	0.78	NPC1 (0.49)	HTTSMN1; SMN2NPC1RAB9AALDH1A1
	SCHEMBL9481208	0.78	NPC1 (0.49)	HTTSMN1; SMN2NPC1RAB9AALDH1A1
	SCHEMBL12371065	0.77	SPHK1 (0.39)	SMN1; SMN2ALDH1A1MEN1KMT2AMAPT
	SCHEMBL2273765	0.77	MAP1LC3B (0.39)	SMN1; SMN2ALDH1A1HPGDATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.