SCHEMBL12371171

SCHEMBL12371171

C[C@@H]1CN(c2ccc(C(F)(F)F)cn2)CC[C@@H]1OS(C)(=O)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.54
GAA P10253 1/20 0.51
KDM4E B2RXH2 2/20 0.50
ABL1 P00519 1/20 0.50
LMNA P02545 1/20 0.50
HRH3 Q9Y5N1 2/20 0.49
HCRTR1 O43613 1/20 0.47
HCRTR2 O43614 1/20 0.47
CA12 O43570 4/20 0.46
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA4 P22748 4/20 0.46
CA7 P43166 4/20 0.46
CA9 Q16790 4/20 0.46
TRPV1 Q8NER1 4/20 0.46
CHRM2 P08172 1/20 0.46
CHRM5 P08912 1/20 0.46
CHRM1 P11229 1/20 0.46
CHRM3 P20309 1/20 0.46
KMT2A Q03164 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6573621 0.86 HRH3 (0.59) GPR119GAAKDM4EABL1LMNA
SCHEMBL757363 0.83 GPR119 (0.61) GPR119GAAKDM4EABL1LMNA
SCHEMBL758277 0.77 KDM4E (0.57) GPR119KDM4EABL1LMNAHRH3
SCHEMBL384718 0.77 KDM4E (0.57) GPR119KDM4EABL1LMNAHRH3
SCHEMBL384719 0.77 KDM4E (0.57) GPR119KDM4EABL1LMNAHRH3
SCHEMBL384717 0.77 KDM4E (0.57) GPR119KDM4EABL1LMNAHRH3
SCHEMBL758278 0.77 KDM4E (0.57) GPR119KDM4EABL1LMNAHRH3
SCHEMBL7250781 0.77 KDM4E (0.58) GPR119GAAKDM4EABL1LMNA
SCHEMBL760736 0.76 KDM4E (0.52) GPR119GAAKDM4EABL1LMNA
SCHEMBL760735 0.76 KDM4E (0.52) GPR119GAAKDM4EABL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7994094-B2 N-pyridylpiperidine compound, method for producing the same, and pest control agent OTSUKA AGRITECHNO CO., LTD. (JP) 2011-08-09 US disclosed
US-20100137582-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT OTSUKA CHEMICAL CO., LTD. (JP) 2010-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137582-A1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT HRH4, NOX4, PRDX4 GPR119 3349/4885GAA 4316/4885KDM4E 471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.