SCHEMBL12371903

SCHEMBL12371903

CCCC(C)Oc1nc2ccccc2s1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.44
PTGS1 P23219 6/20 0.43
PTGS2 P35354 6/20 0.43
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
CASP1 P29466 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
FBP1 P09467 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
MAPT P10636 2/20 0.40
RAB9A P51151 2/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
PAX8 Q06710 1/20 0.40
NOD2 Q9HC29 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30422957 1.00 LOXL2 (0.44) LOXL2PTGS1PTGS2ALOX15TSHR
SCHEMBL2173022 0.90 L3MBTL1 (0.42) LOXL2PTGS1PTGS2ALOX15TSHR
SCHEMBL30423386 0.89 L3MBTL1 (0.41) LOXL2PTGS1PTGS2ALOX15TSHR
SCHEMBL12371902 0.89 L3MBTL1 (0.41) LOXL2PTGS1PTGS2ALOX15TSHR
SCHEMBL18013356 0.88 LOXL2 (0.46) LOXL2PTGS1PTGS2ALOX15TSHR
SCHEMBL2171001 0.87 PPARG (0.55) LOXL2PTGS1PTGS2MEN1KMT2A
SCHEMBL3352036 0.84 PTGS1 (0.43) LOXL2PTGS1PTGS2ALOX15TSHR
SCHEMBL12371897 0.83 TSHR (0.46) LOXL2PTGS1PTGS2ALOX15TSHR
SCHEMBL30423748 0.83 TSHR (0.46) LOXL2PTGS1PTGS2ALOX15TSHR
SCHEMBL11218369 0.80 ALOX15 (0.47) LOXL2PTGS1PTGS2ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN claimed
EP-3464446-B1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2021-06-23 EP claimed
CN-109476874-B Two-part cyanoacrylate curable adhesive systems 汉高知识产权控股有限责任公司 2021-04-16 CN claimed
EP-3464446-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2019-04-10 EP claimed
CN-109476874-A Bi-component cyanoacrylate curable adhesive system 汉高知识产权控股有限责任公司 2019-03-15 CN claimed
US-10100235-B2 Two-part cyanoacrylate curable adhesive system Henkel IP & Holding GmbH (DE) 2018-10-16 US claimed
WO-2017202698-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2017-11-30 WO claimed
US-20170335151-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM HENKEL AG & CO. KGAA (DE) 2017-11-23 US claimed
US-20240318052-A1 METHOD OF UNDERWATER BONDING HENKEL AG & CO KGAA (DE) 2024-09-26 US disclosed
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN disclosed
EP-3464446-B1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2021-06-23 EP disclosed
CN-109476874-B Two-part cyanoacrylate curable adhesive systems 汉高知识产权控股有限责任公司 2021-04-16 CN disclosed
EP-3464446-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2019-04-10 EP disclosed
CN-109476874-A Bi-component cyanoacrylate curable adhesive system 汉高知识产权控股有限责任公司 2019-03-15 CN disclosed
US-20170335151-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM HENKEL AG & CO. KGAA (DE) 2017-11-23 US disclosed
US-8933168-B2 Activators for two part cyanoacrylate adhesives Henkel IP & Holding GmbH (DE) 2015-01-13 US disclosed
US-8933168-B2 Activators for two part cyanoacrylate adhesives Henkel IP & Holding GmbH (DE) 2015-01-13 US disclosed
US-20110196092-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R&D) LIMITED (IE) 2011-08-11 US disclosed
US-20110196092-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R&D) LIMITED (IE) 2011-08-11 US disclosed
WO-2010046412-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R & D) LIMITED (IE) 2010-04-29 WO disclosed