Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12371936 | 0.83 | PRKCA (0.52) | PRKCACTSKCACNA2D1CACNB3CACNA1C | |
| SCHEMBL13654316 | 0.79 | PRKCA (0.36) | PRKCACTSKCACNA2D1CACNB3CACNA1C | |
| SCHEMBL20149745 | 0.78 | PRKCA (0.52) | PRKCA | |
| SCHEMBL106870 | 0.78 | CTSK (0.37) | PRKCACTSKCACNA2D1CACNB3CACNA1C | |
| SCHEMBL9901276 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL17191649 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL454299 | 0.75 | TSHR (0.43) | ADRA1A | |
| SCHEMBL15685105 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL110678 | 0.75 | CTSK (0.36) | PRKCACTSKMMP8 | |
| SCHEMBL12371945 | 0.74 | SCN5A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271683-B1 | POLYMER-DENDRIMER HYBRIDS | UNIV LIVERPOOL (GB) | 2015-09-16 | — | — | EP | disclosed |
| US-8722830-B2 | Polymer-dendrimer hybrids | THE UNIVERSITY OF LIVERPOOL (GB) | 2014-05-13 | — | — | US | disclosed |
| US-8722830-B2 | Polymer-dendrimer hybrids | THE UNIVERSITY OF LIVERPOOL (GB) | 2014-05-13 | — | — | US | disclosed |
| US-20130231450-A1 | POLYMER-DENDRIMER HYBRIDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2013-09-05 | — | — | US | disclosed |
| US-20130231450-A1 | POLYMER-DENDRIMER HYBRIDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2013-09-05 | — | — | US | disclosed |
| US-20110201773-A1 | POLYMER-DENDRIMER HYBRIDS | ULIVE ENTERPRISES LTD. (GB) | 2011-08-18 | — | — | US | disclosed |
| US-20110201773-A1 | POLYMER-DENDRIMER HYBRIDS | ULIVE ENTERPRISES LTD. (GB) | 2011-08-18 | — | — | US | disclosed |