Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12371937 | 0.90 | PRKCA (0.34) | — | |
| SCHEMBL13654589 | 0.78 | CTSK (0.34) | — | |
| SCHEMBL17082791 | 0.75 | CHRM2 (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL13654514 | 0.75 | CHRM2 (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12371942 | 0.74 | PRKCA (0.36) | — | |
| SCHEMBL17805909 | 0.73 | DNM1 (0.40) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL17805908 | 0.70 | DNM1 (0.40) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL17805898 | 0.68 | TSHR (0.40) | — | |
| SCHEMBL22460428 | 0.67 | DNM1 (0.42) | — | |
| SCHEMBL17807355 | 0.67 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722830-B2 | Polymer-dendrimer hybrids | THE UNIVERSITY OF LIVERPOOL (GB) | 2014-05-13 | — | — | US | disclosed |
| US-8722830-B2 | Polymer-dendrimer hybrids | THE UNIVERSITY OF LIVERPOOL (GB) | 2014-05-13 | — | — | US | disclosed |
| US-20130231450-A1 | POLYMER-DENDRIMER HYBRIDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2013-09-05 | — | — | US | disclosed |
| US-20130231450-A1 | POLYMER-DENDRIMER HYBRIDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2013-09-05 | — | — | US | disclosed |
| US-20110201773-A1 | POLYMER-DENDRIMER HYBRIDS | ULIVE ENTERPRISES LTD. (GB) | 2011-08-18 | — | — | US | disclosed |