Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 8/20 | 0.38 |
| ▸ | FEN1 | P39748 | 4/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12373692 | 0.90 | S1PR1 (0.40) | KAT6AFEN1ALOX5APS1PR1S1PR3 | |
| SCHEMBL12373520 | 0.90 | CASP1 (0.39) | SMN1; SMN2NPSR1CASP1MEN1CYP1A2 | |
| SCHEMBL12373631 | 0.89 | KAT6A (0.38) | ALDH1A1SMN1; SMN2NPSR1KAT6AS1PR1 | |
| SCHEMBL12373501 | 0.89 | CYP1A2 (0.41) | ALDH1A1SMN1; SMN2NPSR1CASP1S1PR1 | |
| SCHEMBL12373747 | 0.89 | S1PR1 (0.36) | ALDH1A1SMN1; SMN2NPSR1CASP1FEN1 | |
| SCHEMBL12373584 | 0.89 | KAT6A (0.40) | KAT6AS1PR1S1PR3TP53 | |
| SCHEMBL12373611 | 0.89 | KAT6A (0.40) | SMN1; SMN2NPSR1KAT6AS1PR1S1PR3 | |
| SCHEMBL12373466 | 0.89 | POLB (0.40) | ALDH1A1SMN1; SMN2NPSR1CASP1MEN1 | |
| SCHEMBL12373547 | 0.89 | PGR (0.40) | ALDH1A1CASP1S1PR1S1PR3MEN1 | |
| SCHEMBL12373639 | 0.89 | S1PR1 (0.38) | ALDH1A1SMN1; SMN2NPSR1KAT6AFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994204-B2 | Binding inhibitor of sphingosine-1-phosphate | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-08-09 | — | — | US | disclosed |
| US-7994204-B2 | Binding inhibitor of sphingosine-1-phosphate | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20090182144-A1 | BINDING INHIBITOR OF SPHINGOSINE-1-PHOSPHATE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| US-20090182144-A1 | BINDING INHIBITOR OF SPHINGOSINE-1-PHOSPHATE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182144-A1 | BINDING INHIBITOR OF SPHINGOSINE-1-PHOSPHATE | S1PR1, S1PR3, S1PR2 | ALDH1A1 2969/4885SMN1; SMN2 3091/4885NPSR1 110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.