Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 8/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12373515 | 0.90 | S1PR1 (0.36) | S1PR1ALDH1A1SMN1; SMN2NPSR1S1PR3 | |
| SCHEMBL12373591 | 0.89 | ALDH1A1 (0.38) | KAT6AS1PR1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL12373488 | 0.88 | S1PR1 (0.39) | S1PR1S1PR3P2RX3 | |
| SCHEMBL12373563 | 0.88 | S1PR1 (0.35) | S1PR1S1PR3P2RX3 | |
| SCHEMBL12373463 | 0.86 | MMP13 (0.41) | S1PR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12373634 | 0.86 | PGR (0.41) | S1PR1NPSR1S1PR3 | |
| SCHEMBL12373545 | 0.86 | NR3C1 (0.39) | S1PR1S1PR3P2RX3 | |
| SCHEMBL12373517 | 0.86 | S1PR1 (0.44) | S1PR1ALDH1A1S1PR3 | |
| SCHEMBL12373662 | 0.85 | S1PR1 (0.42) | S1PR1ALDH1A1SMN1; SMN2NPSR1S1PR3 | |
| SCHEMBL12373692 | 0.85 | S1PR1 (0.40) | KAT6AS1PR1S1PR3P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994204-B2 | Binding inhibitor of sphingosine-1-phosphate | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-08-09 | — | — | US | disclosed |
| US-7994204-B2 | Binding inhibitor of sphingosine-1-phosphate | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20090182144-A1 | BINDING INHIBITOR OF SPHINGOSINE-1-PHOSPHATE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| US-20090182144-A1 | BINDING INHIBITOR OF SPHINGOSINE-1-PHOSPHATE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182144-A1 | BINDING INHIBITOR OF SPHINGOSINE-1-PHOSPHATE | S1PR1, S1PR3, S1PR2 | KAT6A 4593/4885S1PR1 1/4885ALDH1A1 2969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.