Ethylene Glycol

Ethylene Glycol

SCHEMBL1237379

C=CCOC(=O)OCC=C.OCCO

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.43
TSHR P16473 7/20 0.41
MAPT P10636 1/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
ALDH1A1 P00352 7/20 0.37
HSD17B10 Q99714 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
NPSR1 Q6W5P4 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
PKM P14618 1/20 0.33
SNCA P37840 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
APP P05067 1/20 0.33
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
MAPK1 P28482 1/20 0.32
GAA P10253 1/20 0.32
RHOA P61586 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL2906369 0.97 CYP3A4 (0.42) CYP3A4TSHRMAPTCACNA1BAPBA1
Ethylene Glycol SCHEMBL1273960 0.97 CYP3A4 (0.42) CYP3A4TSHRMAPTCACNA1BAPBA1
Ethylene Glycol SCHEMBL8369665 0.93 CYP3A4 (0.39) CYP3A4TSHRMAPTCACNA1BAPBA1
Ethylene Glycol SCHEMBL8577362 0.93 TSHR (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL9928 0.92 CYP3A4 (0.48) CYP3A4TSHRMAPTCACNA1BAPBA1
Butane SCHEMBL9110668 0.91 TSHR (0.48) CYP3A4TSHRMAPTCACNA1BAPBA1
1,3-Propanediol SCHEMBL8369666 0.90 TSHR (0.42) CYP3A4TSHRMAPTCACNA1BAPBA1
1,4-Butanediol SCHEMBL21061434 0.90 TSHR (0.42) CYP3A4TSHRMAPTCACNA1BAPBA1
Ethylene Glycol SCHEMBL1923456 0.90 CYP3A4 (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
Ethylene SCHEMBL9717606 0.89 CYP3A4 (0.46) CYP3A4TSHRMAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3448893-B1 COMPOSITION BASED ON ALLYL MONOMERS AND PEROXIDE(S) FOR THE MANUFACTURE OF ORGANIC GLASSES ARKEMA FRANCE (FR) 2024-05-22 EP claimed
EP-1980565-B1 Oil soluble radiation curable metal-containing compositions SARTOMER TECHNOLOGY USA LLC (US) 2011-03-02 EP claimed
EP-1189994-B1 OIL SOLUBLE RADIATION CURABLE METAL-CONTAINING COMPOUNDS AND COMPOSITIONS SARTOMER CO INC (US) 2009-03-18 EP claimed
EP-1980565-A1 Oil soluble radiation curable metal-containing compounds and compositions SARTOMER COMPANY, INC. (US) 2008-10-15 EP claimed
JP-2003501541-A 2003-01-14 JP claimed
US-6399672-B1 OIL SOLUBLE UNSATURATED COMPOUNDS AND PHOTOINITIATORS SARTOMER TECHNOLOGIES CO., INC. 2002-06-04 US claimed
EP-1189994-A2 OIL SOLUBLE RADIATION CURABLE METAL-CONTAINING COMPOUNDS AND COMPOSITIONS SARTOMER COMPANY, INC. (US) 2002-03-27 EP claimed
WO-2000075241-A2 OIL SOLUBLE RADIATION CURABLE METAL-CONTAINING COMPOUNDS AND COMPOSITIONS SARTOMER COMPANY, INC. (US) 2000-12-14 WO claimed
EP-0757699-B1 Low yellow index allylic polymer compositions, polymerizable compositions and lenses made of said compositions ESSILOR INT (FR) 1998-01-07 EP claimed
US-5400175-A Ultraviolet radiation and blue light blocking polarizing lens SUNTIGER, INC. (US) 1995-03-21 US claimed
EP-0292475-A4 ULTRAVIOLET RADIATION AND BLUE LIGHT BLOCKING POLARIZING LENS 1990-09-05 EP claimed
US-4948854-A COPOLYMER INCLUDING ITACONIC ACID DIESTER SEIKO EPSON CORPORATION (JP) 1990-08-14 US claimed
EP-0320954-A2 Transparent resin and transparent resin products NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-06-21 EP claimed
EP-0292475-A1 ULTRAVIOLET RADIATION AND BLUE LIGHT BLOCKING POLARIZING LENS. JOHANSEN LAURIE A (US) 1988-11-30 EP claimed
WO-1988002871-A1 ULTRAVIOLET RADIATION AND BLUE LIGHT BLOCKING POLARIZING LENS SUNTIGER, INCORPORATED (US) 1988-04-21 WO claimed
EP-0242618-A2 Transparent optical article and process for preparing same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-10-28 EP claimed
US-4563416-A NEUTRONS, ALPHA RAYS, COSMIC RAYS TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-01-07 US claimed
EP-0136653-A2 Solid state track detector TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1985-04-10 EP claimed
US-4052520-A PROCESS FOR COATING A SYNTHETIC POLYMER SHEET MATERIAL WITH A DURABLE ABRASION-RESISTANT VITREOUS COMPOSITION AMERICAN OPTICAL CORPORATION (US) 1977-10-04 US claimed
US-3991234-A VACUUM DEPOSITION OF SILICON MONOXIDE AND GLASS AMERICAN OPTICAL CORPORATION (US) 1976-11-09 US claimed