Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RHOA | P61586 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL1273960 | 1.00 | CYP3A4 (0.42) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| Ethylene Glycol SCHEMBL1237379 | 0.97 | CYP3A4 (0.43) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| Ethylene SCHEMBL3010758 | 0.92 | CYP3A4 (0.46) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| Ethylene SCHEMBL9717606 | 0.92 | CYP3A4 (0.46) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| Ethylene Glycol SCHEMBL8369665 | 0.91 | CYP3A4 (0.39) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| Ethylene Glycol SCHEMBL8577362 | 0.91 | TSHR (0.41) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL9928 | 0.89 | CYP3A4 (0.48) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| Butane SCHEMBL9110668 | 0.89 | TSHR (0.48) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| 1,4-Butanediol SCHEMBL21061434 | 0.88 | TSHR (0.42) | CYP3A4TSHRMAPTCACNA1BAPBA1 | |
| Ethylene Glycol SCHEMBL1923456 | 0.88 | CYP3A4 (0.41) | CYP3A4TSHRMAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648130-B2 | Resin composition, transparent member obtained from the resin composition, and use of the same | MITSUI CHEMICALS, INC. (JP) | 2014-02-11 | — | — | US | disclosed |
| US-20100256271-A1 | RESIN COMPOSITION, TRANSPARENT MEMBER OBTAINED FROM THE RESIN COMPOSITION, AND USE OF THE SAME | MITSUI CHEMICALS, INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2223969-A1 | RESIN COMPOSITION, TRANSPARENT MEMBER OBTAINED FROM THE RESIN COMPOSITION, AND USE OF THE SAME | Mitsui Chemicals, Inc. (JP) | 2010-09-01 | — | — | EP | disclosed |
| EP-0590573-B1 | Resin for plastic lens | HITACHI CHEMICAL CO LTD (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5559200-A | POLYMERIZING STYRENE, CYCLOALKYL ACRYLATE OR METHACRYLATE AND CROSSLINKING AGENT, MERCAPTAN OR A-METHYLSTYRENE DIMER MOLECULAR WEIGHT MODIFIER | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5449731-A | Copolymer includes styrene, alicyclic (meth)acrylate, and polyfunctional monomers; transparent; edging ability, low specific gravity, high refractive index; eyeglasses | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0590573-A2 | Resin for plastic lens | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1994-04-06 | — | — | EP | disclosed |