Ethylene Glycol

Ethylene Glycol

SCHEMBL8577362

C=CC.C=CC.C=CCOC(=O)OCC=C.OCCO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 2/20 0.34
NPSR1 Q6W5P4 1/20 0.32
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SNCA P37840 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL1237379 0.93 CYP3A4 (0.43) TSHRCYP3A4TDP1MAPTCACNA1B
Ethylene Glycol SCHEMBL1273960 0.91 CYP3A4 (0.42) TSHRCYP3A4TDP1MAPTCACNA1B
Ethylene Glycol SCHEMBL2906369 0.91 CYP3A4 (0.42) TSHRCYP3A4TDP1MAPTCACNA1B
Butane SCHEMBL9110668 0.89 TSHR (0.48) TSHRCYP3A4TDP1MAPTCACNA1B
Ethylene Glycol SCHEMBL8369665 0.86 CYP3A4 (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL9928 0.85 CYP3A4 (0.48) TSHRCYP3A4TDP1MAPTCACNA1B
Propene SCHEMBL25213417 0.84 ALDH1A1 (0.56) TSHRCYP3A4TDP1MAPTCACNA1B
1,3-Propanediol SCHEMBL8369666 0.84 TSHR (0.42) TSHRCYP3A4TDP1MAPTCACNA1B
1,4-Butanediol SCHEMBL21061434 0.84 TSHR (0.42) TSHRCYP3A4TDP1MAPTCACNA1B
Ethylene Glycol SCHEMBL1923456 0.84 CYP3A4 (0.41) TSHRCYP3A4TDP1MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4563416-A NEUTRONS, ALPHA RAYS, COSMIC RAYS TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-01-07 US claimed
EP-0136653-A2 Solid state track detector TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1985-04-10 EP claimed
US-11639413-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2023-05-02 US disclosed
US-20210017327-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS AND APPLICATION OF SAME MITSUI CHEMICALS, INC. (JP) 2021-01-21 US disclosed
EP-3724700-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS AND APPLICATION OF SAME Mitsui Chemicals, Inc. (JP) 2020-10-21 EP disclosed
US-20190284324-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS AND APPLICATION OF SAME MITSUI CHEMICALS, INC. (JP) 2019-09-19 US disclosed
WO-2019117305-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS AND APPLICATION OF SAME MITSUI CHEMICALS, INC. (JP) 2019-06-20 WO disclosed
US-5730911-A Process for the manufacture of a substrate made of transparent organic glass and substrate thus obtained ESSILOR INTERNATIONAL-COMPAGNIE GENERAL D'OPTIQUE (FR) 1998-03-24 US disclosed
US-4563416-A NEUTRONS, ALPHA RAYS, COSMIC RAYS TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-01-07 US disclosed
EP-0136653-A2 Solid state track detector TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1985-04-10 EP disclosed