Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL1237379 | 0.91 | CYP3A4 (0.43) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| Ethylene Glycol SCHEMBL8577362 | 0.89 | TSHR (0.41) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| Ethylene Glycol SCHEMBL1273960 | 0.89 | CYP3A4 (0.42) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| Ethylene Glycol SCHEMBL2906369 | 0.89 | CYP3A4 (0.42) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| Ethylene Glycol SCHEMBL8369665 | 0.84 | CYP3A4 (0.39) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL9928 | 0.83 | CYP3A4 (0.48) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL18095147 | 0.83 | TSHR (0.48) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL953066 | 0.83 | TSHR (0.48) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| 1,3-Propanediol SCHEMBL8369666 | 0.82 | TSHR (0.42) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL44777 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120186522-A1 | VAPOR DEPOSITION APPARATUS FOR OPTICAL LENS | HOYA CORPORATION (JP) | 2012-07-26 | — | — | US | disclosed |
| EP-2460907-A1 | VAPOR DEPOSITION DEVICE FOR OPTICAL LENSES | Hoya Corporation (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-5350822-A | Divinyl-spirobi/m-dioxane/ | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1994-09-27 | — | — | US | disclosed |