Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374166 | 0.88 | REN (0.54) | RENERAP2ERAP1LNPEPSLC15A2 | |
| SCHEMBL22722176 | 0.82 | REN (0.58) | RENERAP2ERAP1LNPEPSLC15A2 | |
| SCHEMBL27624890 | 0.82 | SLC15A2 (0.61) | RENERAP2ERAP1LNPEPSLC15A2 | |
| SCHEMBL27624690 | 0.80 | SLC15A2 (0.57) | RENERAP2ERAP1LNPEPSLC15A2 | |
| SCHEMBL18862330 | 0.80 | REN (0.55) | RENERAP2ERAP1LNPEPSLC15A2 | |
| SCHEMBL18862042 | 0.79 | REN (0.56) | RENERAP2ERAP1LNPEPSLC15A2 | |
| SCHEMBL18402423 | 0.78 | REN (0.60) | RENERAP2ERAP1LNPEPSLC15A2 | |
| SCHEMBL27624718 | 0.78 | REN (0.51) | RENERAP2ERAP1LNPEPSLC15A2 | |
| SCHEMBL19051548 | 0.78 | REN (0.57) | RENERAP2ERAP1LNPEPSLC15A2 | |
| SCHEMBL16317506 | 0.77 | REN (0.51) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7850947-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2010-12-14 | — | — | US | disclosed |
| US-7850947-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2010-12-14 | — | — | US | disclosed |