SCHEMBL12374342

SCHEMBL12374342

COc1ccc(C2(c3ccc(CO)cc3)c3cc(C)ccc3-c3ccc(C)cc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 8/20 0.44
L3MBTL1 Q9Y468 2/20 0.40
ACHE P22303 1/20 0.38
C3AR1 Q16581 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12374341 0.88 ACHE (0.48) PDE4DL3MBTL1ACHENPC1RAB9A
SCHEMBL13828491 0.87 ACHE (0.52) PDE4DACHEC3AR1ALDH1A1NPC1
SCHEMBL16167856 0.85 ACHE (0.45) PDE4DL3MBTL1ACHENPC1RAB9A
SCHEMBL12545282 0.85 PDE4D (0.43) PDE4DL3MBTL1ALDH1A1NPC1RAB9A
SCHEMBL12830690 0.82 ACHE (0.42) PDE4DL3MBTL1ACHESMN1; SMN2RAB9A
SCHEMBL17885774 0.82 ALOX5 (0.37) PDE4DL3MBTL1RAB9A
SCHEMBL25685552 0.82 PDK2 (0.46) ACHEC3AR1SMN1; SMN2NPC1RAB9A
SCHEMBL17449849 0.81 KMT2A (0.45) PDE4DSMN1; SMN2NPC1RAB9APOLB
SCHEMBL12545359 0.79 PDE4D (0.39) PDE4D
SCHEMBL16234048 0.78 PDK2 (0.50) PDE4DSMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9331284-B2 Polymer compound and light-emitting device using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-05-03 US disclosed
US-9048442-B2 Composition containing a metal complex and organic compound, and light-emitting element using said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-06-02 US disclosed
US-8502209-B2 Polymer compound and organic transistor using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-06 US disclosed
US-20120326140-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-12-27 US disclosed
US-20110187266-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-04 US disclosed
US-20110156018-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-30 US disclosed
US-20110127512-A1 COPOLYMER AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-02 US disclosed
US-20110114890-A1 COMPOSITION CONTAINING A METAL COMPLEX AND ORGANIC COMPOUND, AND LIGHT-EMITTING ELEMENT USING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-19 US disclosed
US-20110073854-A1 POLYMER COMPOUND AND ORGANIC TRANSISTOR USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110073854-A1 POLYMER COMPOUND AND ORGANIC TRANSISTOR USING THE SAME TERT, NOXO1, TERB1 PDE4D 4784/4885L3MBTL1 1506/4885ACHE 3114/4885
US-20120326140-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING SAME CCNA1, CCNB1, CCNL2 PDE4D 4180/4885L3MBTL1 28/4885ACHE 2098/4885
US-20110156018-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME CCNL2, ARL1, RIF1 PDE4D 4885/4885L3MBTL1 618/4885ACHE 4242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.