SCHEMBL12374394

SCHEMBL12374394

Cc1ccc(-c2cc(-c3ccc(-c4cc(-c5ccc(C)cc5)c(C)s4)c4nsnc34)sc2C)cc1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ USP2 O75604 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ COMT P21964 1/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ RPS6KA3 P51812 1/20 0.31
▸ ESR1 P03372 1/20 0.30
▸ ESR2 Q92731 1/20 0.30
▸ NPC1 O15118 1/20 0.30
▸ RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12545076 0.87 PLA2G10 (0.39) LMNAMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL12374391 0.85 APP (0.41) MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL12544949 0.81 ESR1 (0.41) LMNAMEN1KMT2AGAAMAPT
SCHEMBL862821 0.80 COMT (0.40) LMNAMEN1KMT2AUSP2GAA
SCHEMBL12545244 0.79 PLA2G10 (0.36) ESR1ESR2
SCHEMBL15599510 0.79 LMNA (0.33) LMNAMEN1KMT2AUSP2GAA
SCHEMBL20806202 0.79 COMT (0.39) LMNAMEN1KMT2AUSP2GAA
SCHEMBL11887463 0.78 HSD17B1 (0.38) LMNAMEN1KMT2AUSP2GAA
SCHEMBL12374389 0.78 ESR2 (0.36) MEN1KMT2AMAPTALDH1A1ESR1
SCHEMBL12544768 0.76 ESR1 (0.42) LMNAMEN1KMT2AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9331284-B2 Polymer compound and light-emitting device using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-05-03 — — US disclosed
US-20120326140-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-12-27 — — US disclosed
US-20110187266-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120326140-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING SAME CCNA1, CCNB1, CCNL2 LMNA 668/4885MEN1 2260/4885KMT2A 817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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