Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.38 |
| ▸ | APP | P05067 | 7/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26500050 | 0.88 | ENPP1 (0.36) | GAAMAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL15599510 | 0.86 | LMNA (0.33) | HSD17B1HSD17B2LMNAGAAMAPT | |
| SCHEMBL4754949 | 0.84 | CYP2D6 (0.46) | LMNAMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL26500046 | 0.82 | HSD17B1 (0.45) | HSD17B1HSD17B2APPESR2ESR1 | |
| SCHEMBL21846604 | 0.82 | APP (0.61) | HSD17B1HSD17B2APPESR2ESR1 | |
| SCHEMBL14515076 | 0.81 | HSD17B1 (0.44) | HSD17B1HSD17B2APPESR2ESR1 | |
| SCHEMBL25070495 | 0.81 | APP (0.56) | HSD17B1HSD17B2APPESR2ESR1 | |
| SCHEMBL14515083 | 0.81 | NPC1 (0.38) | APPESR2ESR1LMNAKMT2A | |
| SCHEMBL12587556 | 0.81 | ESR2 (0.38) | APPESR2ESR1MAPTMEN1 | |
| SCHEMBL19636785 | 0.81 | HSD17B1 (0.33) | HSD17B1HSD17B2ESR2ESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160319592-A1 | DEVICE FOR REGULATING THE PASSAGE OF LIGHT | MERCK PATENT GMBH (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20160108317-A1 | DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY, CONTAINING A DICHROIC DYE COMPOUND | MERCK PATENT GMBH (DE) | 2016-04-21 | — | — | US | disclosed |
| US-8664645-B2 | Organic electroluminescence element and display medium | FUJI XEROX CO., LTD. (JP) | 2014-03-04 | — | — | US | disclosed |
| US-8664645-B2 | Organic electroluminescence element and display medium | FUJI XEROX CO., LTD. (JP) | 2014-03-04 | — | — | US | disclosed |
| US-20120187384-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND DISPLAY MEDIUM | FUJI XEROX CO., LTD. (JP) | 2012-07-26 | — | — | US | disclosed |
| US-20120187384-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND DISPLAY MEDIUM | FUJI XEROX CO., LTD. (JP) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108317-A1 | DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY, CONTAINING A DICHROIC DYE COMPOUND | CRY1, SLC25A1, CRY2 | HSD17B1 1601/4885HSD17B2 1244/4885APP 1959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.