Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | NQO1 | P15559 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2278731 | 0.87 | PADI4 (0.50) | PADI4ALDH1A1KDM4EABCG2NQO1 | |
| SCHEMBL2278736 | 0.87 | PADI4 (0.50) | PADI4ALDH1A1KDM4EABCG2NQO1 | |
| SCHEMBL2284378 | 0.85 | ALDH1A1 (0.47) | PADI4ALDH1A1KDM4EABCG2NQO1 | |
| SCHEMBL2284384 | 0.85 | ALDH1A1 (0.47) | PADI4ALDH1A1KDM4EABCG2NQO1 | |
| SCHEMBL2280086 | 0.85 | PADI4 (0.48) | PADI4ALDH1A1KDM4EABCG2NQO1 | |
| SCHEMBL2280088 | 0.85 | PADI4 (0.48) | PADI4ALDH1A1KDM4EABCG2NQO1 | |
| SCHEMBL12374839 | 0.82 | ABCG2 (0.45) | ALDH1A1KDM4EABCG2NQO1NPC1 | |
| SCHEMBL13403233 | 0.79 | NQO1 (0.61) | ALDH1A1KDM4EABCG2NQO1MEN1 | |
| SCHEMBL12374662 | 0.79 | PADI4 (0.47) | PADI4KDM4EABCG2NQO1MEN1 | |
| SCHEMBL2279338 | 0.76 | PADI4 (0.53) | PADI4ALDH1A1KDM4EABCG2NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989478-B2 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-02 | — | — | US | disclosed |