SCHEMBL1237656

SCHEMBL1237656

O=C(O)Cn1ncnn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18839855 0.75 ALDH1A1 (0.40)
SCHEMBL908783 0.70
SCHEMBL503133 0.70 GRIA1 (0.41)
SCHEMBL2824372 0.70 POLB (0.33)
Hydrochloric Acid SCHEMBL1372426 0.69 ALDH1A1 (0.41)
SCHEMBL1179541 0.68 L3MBTL1 (0.35)
SCHEMBL11675118 0.66 POLB (0.35)
Propionic Acid SCHEMBL18668396 0.65 FFAR3 (0.42)
Formic Acid SCHEMBL27719201 0.65 POLB (0.32)
Propionic Acid SCHEMBL28802772 0.64 FFAR3 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105814702-B Curable organosilicon composition and optical semiconductor device 道康宁东丽株式会社 2018-06-26 CN claimed
US-9691951-B2 Curable silicone composition, and optical semiconductor device DOW CORNING TORAY CO., LTD. (JP) 2017-06-27 US claimed
EP-3059768-A1 CURABLE SILICONE COMPOSITION, AND OPTICAL SEMICONDUCTOR DEVICE Dow Corning Toray Co., Ltd. (JP) 2016-08-24 EP claimed
US-20160233395-A1 Curable Silicone Composition, And Optical Semiconductor Device DOW TORAY CO., LTD. (JP) 2016-08-11 US claimed
CN-105814702-A Curable silicone composition, and optical semiconductor device 道康宁东丽株式会社 2016-07-27 CN claimed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-20210161869-A1 ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2021-06-03 US disclosed
US-10966967-B2 Aryl dihydropyridinones and piperidinone MGAT2 inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2021-04-06 US disclosed
US-20200281905-A1 ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2020-09-10 US disclosed
CN-107266416-B Aryldihydropyridinones and piperidones as MGAT2 inhibitors 百时美施贵宝公司 2020-07-10 CN disclosed
US-10695328-B2 Aryl dihydropyridinones and piperidinone MGAT2 inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2020-06-30 US disclosed
US-20190314346-A1 ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2019-10-17 US disclosed
US-4179511-A Antibacterial 3-(5-tetrazolyl) penam compounds PFIZER INC. (US) 1979-12-18 US disclosed
US-4172199-A ISOOXACEPHALOSPORINS BRISTOL-MYERS COMPANY (US) 1979-10-23 US disclosed
US-4143039-A ANTIBACTERIAL 3-(5-TETRAZOLYL)PENAM COMPOUNDS PFIZER INC. (US) 1979-03-06 US disclosed
US-4115385-A PENICILLINS PFIZER INC. (US) 1978-09-19 US disclosed
US-4113946-A Δ2,3 -1,4-Morpholine-2-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1978-09-12 US disclosed
US-4066831-A ANTIBIOTICS BRISTOL-MYERS COMPANY (US) 1978-01-03 US disclosed
US-4065623-A O-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1977-12-27 US disclosed
US-4012383-A BACTERICIDES BRISTOL-MYERS COMPANY (US) 1977-03-15 US disclosed