SCHEMBL123766

SCHEMBL123766

CCOC(=O)C(C(C)=O)C(C)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
LMNA P02545 1/20 0.52
HSD17B10 Q99714 1/20 0.52
ALOX15 P16050 1/20 0.43
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
SOAT1 P35610 1/20 0.43
MAPT P10636 1/20 0.40
TRPA1 O75762 1/20 0.40
GLO1 Q04760 1/20 0.39
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
TSHR P16473 1/20 0.37
PIN1 Q13526 1/20 0.36
HPGD P15428 1/20 0.36
AURKA O14965 1/20 0.36
NTRK1 P04629 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28190143 0.97 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL29866763 0.95 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL26302 0.94 ALDH1A1 (0.52) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL28266492 0.90 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL1012864 0.87 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL3303175 0.85 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL11580142 0.85 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL14375225 0.85 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL14375227 0.85 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL425250 0.85 ALDH1A1 (0.56) ALDH1A1LMNAHSD17B10ALOX15MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 419 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12303574-B2 Dental composition Dentslpy Sirona Inc. (US) 2025-05-20 US claimed
CN-119978006-A Preparation of host-guest doped TADF nano-particles and application of host-guest doped TADF nano-particles in STED imaging 中国农业大学 2025-05-13 CN claimed
CN-119709111-A Dealcoholized single-component transparent organic silicon sealant and preparation method thereof 广州白云科技股份有限公司 2025-03-28 CN claimed
CN-114449989-B Dental composition 登士柏希罗纳有限公司 2024-10-15 CN claimed
CN-114478500-B Coumarin two-photon initiator and synthesis method and application thereof 浙江大学 2024-03-29 CN claimed
CN-114836164-B Silane modified bio-based polyurethane waterproof sealant and preparation method thereof 郑州华普密封材料有限公司 2024-02-23 CN claimed
US-20230000727-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2023-01-05 US claimed
EP-4021373-A1 DENTAL COMPOSITION Dentsply Sirona Inc. (US) 2022-07-06 EP claimed
CN-114449989-A Dental composition 登士柏希罗纳有限公司 2022-05-06 CN claimed
WO-2021037396-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2021-03-04 WO claimed
CN-102713756-B Light-sensitive polymer composition, method for producing pattern, and electronic component HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) 2014-10-15 CN claimed
CN-102300904-A Method for producing polylactic acid 2011-12-28 CN claimed
CN-101565596-B Neutral silicone weather resistant glue formula and technique for preparing the same SHENZHEN BAILICHUN VISCOSE INDUSTRY CO LTD 2011-07-13 CN claimed
CN-101189274-B Latent curing agent SONY CHEM & INF DEVICE CORP 2011-05-25 CN claimed
CN-101565596-A Neutral silicone weather resistant glue formula and technique for preparing the same SHENZHEN BAILICHUN VISCOSE IND (CN) 2009-10-28 CN claimed
US-7560550-B2 Method for the production of OH protected[4-(2.6-diamino-9H-purine-9-yl)-1.3-dioxolane-2-yl]methanol derivatives RFS PHARMA, LLC (US) 2009-07-14 US claimed
CN-101189274-A Latent curing agent SONY CHEM & INF DEVICE CORP (JP) 2008-05-28 CN claimed
EP-0912467-B1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE SA (FR) 2002-04-24 EP claimed
EP-0912467-A1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE (FR) 1999-05-06 EP claimed
WO-1998000375-A1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE (FR) 1998-01-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000727-A1 DENTAL COMPOSITION ERCC1, CROCC, CAD ALDH1A1 326/4885LMNA 1200/4885HSD17B10 571/4885
US-12303574-B2 Dental composition ERCC1, INTS9, CLINT1 ALDH1A1 721/4885LMNA 1212/4885HSD17B10 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.