Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26302 | 0.87 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL662792 | 0.87 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL123766 | 0.87 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL28163656 | 0.87 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL28190143 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL28266492 | 0.83 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL29866763 | 0.83 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL10880659 | 0.80 | ALDH1A1 (0.56) | ALDH1A1LMNAHCAR2MAPTCYP2D6 | |
| SCHEMBL23255870 | 0.80 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL26657820 | 0.80 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10ALOX15MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101747336-B | Novel method for synthesizing Repirinast | JIANGSU JUMPCAN MEDICINES CO LTD | 2012-07-18 | — | — | CN | claimed |
| US-4064122-A | Hydroxy-substituted cephalosporins | ISHIMARU TOSHIYASU | 1977-12-20 | — | — | US | claimed |
| JP-7267942-A | — | — | None | — | — | JP | disclosed |
| US-20220054658-A1 | CONJUGATES | TRANSFECTION HOLDINGS LIMITED (NZ) | 2022-02-24 | — | — | US | disclosed |
| EP-3897737-A1 | CONJUGATES | Transfection Holdings Limited (NZ) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020127602-A1 | CONJUGATES | TRANSFECTION HOLDINGS LIMITED (NZ) | 2020-06-25 | — | — | WO | disclosed |
| CN-101747336-B | Novel method for synthesizing Repirinast | JIANGSU JUMPCAN MEDICINES CO LTD | 2012-07-18 | — | — | CN | disclosed |
| EP-1118674-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE | NIHON MEDIPHYSICS CO LTD (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-6660863-B2 | Reacting an cycloheptatriene nitrile compound with nortropane compound | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-12-09 | — | — | US | disclosed |
| US-6596868-B2 | Reacting a cycloheptatriene derivative with a primary amine or ammonia in the presence of a base | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |
| US-20030109708-A1 | Process for synthesizing anhydroecgonine derivative | NIHON MEDI-PHYSICS CO., LTD. | 2003-06-12 | — | — | US | disclosed |
| US-6486323-B1 | Process for producing optically active tropinonemonocarboxylic acid derivative | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2002-11-26 | — | — | US | disclosed |
| US-20010020096-A1 | Process for synthesizing anhydroecgonine derivative | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2001-09-06 | — | — | US | disclosed |
| EP-1127887-A1 | Process for synthesizing anhydroecgonine derivative | NIHON MEDI-PHYSICS Co., Ltd. (JP) | 2001-08-29 | — | — | EP | disclosed |
| EP-1118674-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE | Nihon Medi-Physics Co., Ltd. (JP) | 2001-07-25 | — | — | EP | disclosed |
| JP-H07267942-A | BIS(3-(4-SUBSTITUTED COUMARYL))KETONE COMPOUND AND PHOTOSENSITIZER | MITSUI TOATSU CHEM INC | 1995-10-17 | — | — | JP | disclosed |
| EP-0022482-B1 | PROCESS FOR PREPARING 4-HYDROXY-3-METHYL-2-(2-PROPYNYL)-2-CYCLOPENTENOLONE; A GAMMA-DIKETONE COMPOUND AND SUBSTITUTED ACETONEDICARBOXYLIC ESTERS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-09-14 | — | — | EP | disclosed |
| US-4343953-A | STARTING WITH A 3-OXO-GLUTARATE AND 3-CHLOROPROPYNE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-08-10 | — | — | US | disclosed |
| EP-0022482-A2 | Process for preparing 4-hydroxy-3-methyl-2-(2-propynyl)-2-cyclopentenolone; a gamma-diketone compound and substituted acetonedicarboxylic esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-01-21 | — | — | EP | disclosed |
| US-4102688-A | CONTAINING PYRAZOLO(3,4-B)PYRIDINE/3,6-DIONE MOIETY | FUJI PHOTO FILM CO., LTD. (JP) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109708-A1 | Process for synthesizing anhydroecgonine derivative | CES2, NPR1, OPRL1 | ALDH1A1 739/4885LMNA 3660/4885HSD17B10 462/4885 |
| US-20220054658-A1 | CONJUGATES | RTN3, RER1, HRH4 | ALDH1A1 74/4885LMNA 1704/4885HSD17B10 752/4885 |
| US-20010020096-A1 | Process for synthesizing anhydroecgonine derivative | CES2, NPR1, OPRL1 | ALDH1A1 739/4885LMNA 3660/4885HSD17B10 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.