SCHEMBL12376687

SCHEMBL12376687

C=C(C)C(=O)OC1C2OC(=O)C3C2OC1C3C(=O)Oc1ccc([S+](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.35
GPX4 P36969 1/20 0.32
HTT P42858 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
FABP7 O15540 1/20 0.31
FABP3 P05413 1/20 0.31
FABP5 Q01469 1/20 0.31
P4HB P07237 1/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14209186 0.83 KMT2A (0.30) HTTKDM4ENPC1POLBMAPT
SCHEMBL12376688 0.83 ELANE (0.36) ELANEGPX4HTTKDM4ENPC1
SCHEMBL92239 0.78 KDM4E (0.34) GPX4HTTKDM4ENPC1POLB
SCHEMBL16372800 0.78 KDM4E (0.34) GPX4HTTKDM4ENPC1POLB
SCHEMBL17717421 0.78 KDM4E (0.32) GPX4HTTKDM4ENPC1POLB
SCHEMBL11976384 0.78 GPX4 (0.31) GPX4HTTKDM4ENPC1POLB
SCHEMBL13305174 0.77 CYP2D6 (0.34) NPC1POLBMAPTRAB9AGAA
SCHEMBL17717402 0.76 KDM4E (0.33) GPX4HTTKDM4ENPC1POLB
SCHEMBL13435955 0.72 FABP7 (0.34) HTTKDM4ENPC1POLBMAPT
SCHEMBL13435958 0.72 KDM4E (0.31) HTTKDM4ENPC1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8691490-B2 Sulfonium salt, polymer, method for producing the polymer, resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-04-08 US disclosed
US-20110189607-A1 NOVEL SULFONIUM SALT, POLYMER, METHOD FOR PRODUCING THE POLYMER, RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110189607-A1 NOVEL SULFONIUM SALT, POLYMER, METHOD FOR PRODUCING THE POLYMER, RESIST COMPOSITION AND PATTERNING PROCESS RPS4Y1, ETV6, RPS4X ELANE 288/4885GPX4 4461/4885HTT 2417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.