SCHEMBL12376721

SCHEMBL12376721

Cc1ccc(C)c(NC(=O)c2cc(Cl)c3ccccc3c2O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TNF P01375 1/20 0.71
▸ NOD1 Q9Y239 1/20 0.71
▸ RAB9A P51151 5/20 0.61
▸ LMNA P02545 5/20 0.61
▸ HSD17B10 Q99714 2/20 0.61
▸ TSHR P16473 1/20 0.61
▸ MEN1 O00255 4/20 0.55
▸ KMT2A Q03164 4/20 0.55
▸ POLB P06746 3/20 0.55
▸ GAA P10253 1/20 0.55
▸ ALDH1A1 P00352 2/20 0.54
▸ NPSR1 Q6W5P4 2/20 0.54
▸ KDM4E B2RXH2 3/20 0.53
▸ MAPT P10636 3/20 0.51
▸ HTT P42858 3/20 0.51
▸ PKM P14618 1/20 0.51
▸ HPGD P15428 1/20 0.51
▸ NPC1 O15118 3/20 0.49
▸ MAOA P21397 1/20 0.49
▸ MAOB P27338 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14577468 0.86 TNF (0.67) TNFNOD1RAB9ALMNAHSD17B10
SCHEMBL14611628 0.85 MEN1 (0.56) TNFNOD1HSD17B10TSHRMEN1
SCHEMBL14422306 0.77 CYP1A2 (0.56) TNFNOD1RAB9ALMNAMEN1
SCHEMBL11606786 0.77 RAB9A (0.55) TNFNOD1RAB9AMEN1KMT2A
SCHEMBL13656899 0.76 MEN1 (0.66) TNFNOD1RAB9ALMNAHSD17B10
SCHEMBL11400333 0.76 LMNA (1.00) RAB9ALMNAHSD17B10TSHRMEN1
SCHEMBL12270570 0.76 MEN1 (0.51) TNFNOD1RAB9ALMNAHSD17B10
SCHEMBL11595676 0.76 RAB9A (0.56) RAB9ALMNAHSD17B10TSHRMEN1
SCHEMBL14567628 0.74 RAB9A (0.56) TNFNOD1RAB9ALMNAMEN1
SCHEMBL7821474 0.74 NPSR1 (0.76) RAB9ALMNAHSD17B10TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8409792-B2 Color intermediate motion picture film EAST KODAK COMPANY (US) 2013-04-02 — — US disclosed
US-7998665-B2 Color intermediate motion picture film EASTMAN KODAK COMPANY (US) 2011-08-16 — — US disclosed
US-20110136065-A1 COLOR INTERMEDIATE MOTION PICTURE FILM QUALEX INC. 2011-06-09 — — US disclosed
US-20100167218-A1 COLOR INTERMEDIATE MOTION PICTURE FILM EASTMAN KODAK COMPANY 2010-07-01 — — US disclosed
US-20090325108-A1 COLOR PHOTOGRAPHIC MATERIALS WITH MAGENTA MINIMUM DENSITY DYES LASER PACIFIC MEDIA CORPORATION 2009-12-31 — — US disclosed
US-7632632-B1 Color photographic materials with magenta minimum density dyes EASTMAN KODAK COMPANY (US) 2009-12-15 — — US disclosed
US-7629112-B1 Color photographic materials with yellow minimum density colorants EASTMAN KODAK COMPANY (US) 2009-12-08 — — US disclosed
US-20090297992-A1 COLOR PHOTOGRAPHIC MATERIALS WITH YELLOW MINIMUM DENSITY COLORANTS KODAK (NEAR EAST) INC. 2009-12-03 — — US disclosed
US-20090233247-A1 INFRARED DYE FOR SILVER HALIDE-BASED PHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY 2009-09-17 — — US disclosed
US-20090234131-A1 INFRARED DYE FOR SILVER HALIDE-BASED PHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY (US) 2009-09-17 — — US disclosed
US-7175975-B2 Photographic material with improved development inhibitor releases EASTMAN KODAK COMPANY (US) 2007-02-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090234131-A1 INFRARED DYE FOR SILVER HALIDE-BASED PHOTOGRAPHIC ELEMENTS IK, HTT, HYPK TNF 1462/4885NOD1 1037/4885RAB9A 2873/4885
US-20090233247-A1 INFRARED DYE FOR SILVER HALIDE-BASED PHOTOGRAPHIC ELEMENTS IK, HYPK, HTT TNF 2273/4885NOD1 1071/4885RAB9A 3063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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