SCHEMBL12376725

SCHEMBL12376725

C=C(C)C(=O)Oc1cc2ccccc2cc1C(=O)Oc1ccc([S+](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.47
POLB P06746 2/20 0.41
MAPT P10636 9/20 0.40
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 4/20 0.40
HPGD P15428 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
MAPK1 P28482 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TP53 P04637 1/20 0.36
ATM Q13315 1/20 0.36
PTGS2 P35354 1/20 0.36
HSP90AA1 P07900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12376705 0.86 ELANE (0.50) ELANEMAPTALDH1A1KDM4EHPGD
SCHEMBL92378 0.82 ELANE (0.66) ELANEPOLBMAPTALDH1A1TDP1
SCHEMBL12376710 0.81 ELANE (0.43) ELANEPOLBMAPTALDH1A1KDM4E
SCHEMBL12376716 0.80 ELANE (0.64) ELANEMAPTALDH1A1KDM4EHPGD
SCHEMBL12376727 0.79 KDM4E (0.55) POLBMAPTALDH1A1KDM4EHPGD
SCHEMBL12376709 0.79 ELANE (0.56) ELANEPOLBMAPTALDH1A1KDM4E
SCHEMBL12376708 0.78 ELANE (0.57) ELANEPOLBMAPTALDH1A1TDP1
SCHEMBL12458543 0.76 ELANE (0.54) ELANEPOLBMAPTALDH1A1KDM4E
SCHEMBL21526685 0.74 HSD17B10 (0.56) ELANEMAPTALDH1A1KDM4EHPGD
SCHEMBL1801152 0.73 ELANE (0.49) ELANEPOLBMAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8691490-B2 Sulfonium salt, polymer, method for producing the polymer, resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-04-08 US disclosed
US-20110189607-A1 NOVEL SULFONIUM SALT, POLYMER, METHOD FOR PRODUCING THE POLYMER, RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110189607-A1 NOVEL SULFONIUM SALT, POLYMER, METHOD FOR PRODUCING THE POLYMER, RESIST COMPOSITION AND PATTERNING PROCESS RPS4Y1, ETV6, RPS4X ELANE 288/4885POLB 1380/4885MAPT 3052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.