SCHEMBL12376727

SCHEMBL12376727

C=C(C)C(=O)Oc1ccc2oc(=O)c(C(=O)Oc3ccc([S+](c4ccccc4)c4ccccc4)cc3)cc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.55
ALDH1A1 P00352 4/20 0.55
NPSR1 Q6W5P4 1/20 0.55
POLB P06746 1/20 0.54
MAPT P10636 3/20 0.53
F2 P00734 3/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
HTT P42858 1/20 0.49
CACNA1B Q00975 1/20 0.49
APBA1 Q02410 1/20 0.49
F12 P00748 5/20 0.48
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
HPGD P15428 1/20 0.46
CA6 P23280 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12376725 0.79 ELANE (0.47) KDM4EALDH1A1NPSR1POLBMAPT
SCHEMBL12376709 0.78 ELANE (0.56) KDM4EALDH1A1POLBMAPTMEN1
SCHEMBL2305358 0.77 GAPDH (0.66) KDM4EALDH1A1MEN1KMT2AMAOB
SCHEMBL92378 0.77 ELANE (0.66) ALDH1A1NPSR1POLBMAPTKMT2A
SCHEMBL12376705 0.75 ELANE (0.50) KDM4EALDH1A1NPSR1MAPTCYP2C9
SCHEMBL12376716 0.75 ELANE (0.64) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL12376708 0.74 ELANE (0.57) ALDH1A1POLBMAPTMEN1KMT2A
SCHEMBL12735024 0.74 GAPDH (0.77) KDM4EMEN1KMT2ACA1CA2
SCHEMBL14652690 0.73 ALDH1A1 (0.75) KDM4EALDH1A1NPSR1POLBMAPT
SCHEMBL15733005 0.72 KDM4E (0.79) KDM4EALDH1A1NPSR1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8691490-B2 Sulfonium salt, polymer, method for producing the polymer, resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-04-08 US disclosed
US-20110189607-A1 NOVEL SULFONIUM SALT, POLYMER, METHOD FOR PRODUCING THE POLYMER, RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110189607-A1 NOVEL SULFONIUM SALT, POLYMER, METHOD FOR PRODUCING THE POLYMER, RESIST COMPOSITION AND PATTERNING PROCESS RPS4Y1, ETV6, RPS4X KDM4E 2302/4885ALDH1A1 4540/4885NPSR1 1114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.