SCHEMBL12376963

SCHEMBL12376963

COc1ccc(C(C)c2ccc(OC(=O)c3ccc(Oc4ccc(C(C)=O)cc4)cc3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.53
▸ HPGD P15428 1/20 0.53
▸ RAB9A P51151 1/20 0.53
▸ KMT2A Q03164 7/20 0.50
▸ LMNA P02545 2/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CYP2C9 P11712 1/20 0.50
▸ CYP2C19 P33261 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ GAA P10253 1/20 0.49
▸ PRSS1 P07477 2/20 0.48
▸ ACR P10323 2/20 0.48
▸ GFER P55789 1/20 0.48
▸ PARP10 Q53GL7 1/20 0.46
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ BACE1 P56817 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12404369 0.96 LMNA (0.54) MAPTKMT2ALMNACYP1A2CYP2C9
SCHEMBL18230886 0.92 KMT2A (0.50) MAPTKMT2ALMNACYP1A2CYP2C9
SCHEMBL12376950 0.90 MAPT (0.66) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL12376956 0.90 MAPT (0.66) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL19763411 0.90 MAPT (0.66) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL11911280 0.90 MAPT (0.66) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL18230893 0.88 KMT2A (0.49) MAPTRAB9AKMT2ALMNACYP1A2
SCHEMBL13324835 0.88 KMT2A (0.49) MAPTRAB9AKMT2ALMNACYP1A2
SCHEMBL12404382 0.87 KMT2A (0.47) MAPTHPGDRAB9AKMT2ALMNA
SCHEMBL21935947 0.87 MAPT (0.53) MAPTHPGDRAB9AKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9746816-B2 Image forming apparatus and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-29 — — US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 — — US disclosed
US-9494883-B2 Electrophotographic photoreceptor and resin composition IDEMITSU KOSAN CO., LTD. (JP) 2016-11-15 — — US disclosed
US-20110206411-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-25 — — US disclosed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 — — US disclosed
US-20110013934-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 — — US disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 — — US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 — — US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 — — US disclosed
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