Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | ACR | P10323 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230893 | 1.00 | KMT2A (0.49) | KMT2ASMN1; SMN2LMNACYP1A2CYP2C9 | |
| SCHEMBL12404369 | 0.92 | LMNA (0.54) | KMT2ASMN1; SMN2LMNACYP1A2CYP2C9 | |
| SCHEMBL12762440 | 0.91 | KMT2A (0.59) | KMT2ASMN1; SMN2LMNACYP1A2CYP2C9 | |
| SCHEMBL12895879 | 0.91 | KMT2A (0.59) | KMT2ASMN1; SMN2LMNACYP1A2CYP2C9 | |
| SCHEMBL12376963 | 0.88 | MAPT (0.53) | KMT2ASMN1; SMN2LMNACYP1A2CYP2C9 | |
| SCHEMBL18230886 | 0.88 | KMT2A (0.50) | KMT2ASMN1; SMN2LMNACYP1A2CYP2C9 | |
| SCHEMBL12376965 | 0.87 | KMT2A (0.54) | KMT2ASMN1; SMN2LMNACYP1A2CYP2C9 | |
| SCHEMBL12903836 | 0.86 | L3MBTL1 (0.47) | KMT2ACYP1A2CYP2C9MAPTGAA | |
| SCHEMBL13324838 | 0.84 | KMT2A (0.46) | KMT2AMAPTGAAALDH1A1MEN1 | |
| SCHEMBL21935947 | 0.83 | MAPT (0.53) | KMT2ASMN1; SMN2LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718337-B2 | Electrophotographic photoreceptor | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-05-18 | — | — | US | disclosed |
| US-20090081570-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-03-26 | — | — | US | disclosed |