SCHEMBL12376956

SCHEMBL12376956

COc1ccc(Oc2ccc(OC(=O)c3ccc(Oc4ccc(C(C)=O)cc4)cc3)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.66
▸ HPGD P15428 1/20 0.66
▸ RAB9A P51151 1/20 0.66
▸ LMNA P02545 2/20 0.60
▸ CYP1A2 P05177 1/20 0.60
▸ CYP2C9 P11712 1/20 0.60
▸ CYP2C19 P33261 1/20 0.60
▸ SMN1; SMN2 Q16637 1/20 0.60
▸ KMT2A Q03164 9/20 0.59
▸ GFER P55789 1/20 0.56
▸ PRSS1 P07477 1/20 0.56
▸ ACR P10323 1/20 0.56
▸ CA1 P00915 2/20 0.56
▸ CA2 P00918 2/20 0.56
▸ PARP10 Q53GL7 1/20 0.56
▸ KDM4E B2RXH2 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ CES2 O00748 1/20 0.50
▸ CES1 P23141 1/20 0.50
▸ BACE1 P56817 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12376950 1.00 MAPT (0.66) MAPTHPGDRAB9ALMNACYP1A2
SCHEMBL19763411 1.00 MAPT (0.66) MAPTHPGDRAB9ALMNACYP1A2
SCHEMBL11911280 1.00 MAPT (0.66) MAPTHPGDRAB9ALMNACYP1A2
SCHEMBL12376955 0.95 MAPT (0.59) MAPTHPGDRAB9ALMNACYP1A2
SCHEMBL11911278 0.95 LMNA (0.66) MAPTHPGDRAB9ALMNACYP1A2
SCHEMBL12376965 0.91 KMT2A (0.54) MAPTHPGDRAB9ALMNACYP1A2
SCHEMBL12762443 0.91 MAPT (0.54) MAPTHPGDRAB9ALMNACYP1A2
SCHEMBL12376961 0.90 MAPT (0.53) MAPTHPGDRAB9ALMNACYP1A2
SCHEMBL12376963 0.90 MAPT (0.53) MAPTHPGDRAB9ALMNACYP1A2
SCHEMBL15854280 0.90 LMNA (0.60) MAPTHPGDRAB9ALMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9746816-B2 Image forming apparatus and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-29 — — US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 — — US disclosed
US-9091912-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-07-28 — — US disclosed
US-20110206411-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-25 — — US disclosed
US-7901855-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2011-03-08 — — US disclosed
US-7875410-B2 capable opersistently exerting effect of mitigating contact stress with contact members and improved potential stability during repeated use; polycarbonates CANON KABUSHIKI KAISHA (JP) 2011-01-25 — — US disclosed
US-20100092208-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 — — US disclosed
US-20100092209-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 — — US disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 — — US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 — — US disclosed
Send feedback