Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12313843 | 0.88 | TSHR (0.46) | TSHRMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4270081 | 0.88 | TSHR (0.46) | TSHRMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19560737 | 0.86 | NAAA (0.47) | TSHRMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7264567 | 0.86 | SMN1; SMN2 (0.48) | TSHRMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20822014 | 0.86 | MEN1 (0.48) | TSHRMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12285997 | 0.85 | MEN1 (0.52) | TSHRMAPK1MEN1KMT2ALMNA | |
| SCHEMBL12752075 | 0.85 | GAA (0.47) | TSHRMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1415986 | 0.85 | TSHR (0.42) | TSHRMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20244904 | 0.85 | CA2 (0.48) | TSHRMAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21925689 | 0.83 | TSHR (0.50) | TSHRMAPK1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2030966-B1 | BENZYLIDENE MALONAMIDE AND SALT THEREOF, ULTRAVIOLET RAY ABSORBENT, AND AGENT FOR EXTERNAL APPLICATION TO THE SKIN | SHISEIDO CO LTD (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-8003083-B2 | Benzylidene malonamide and salt thereof, ultraviolet ray absorbent, and agent for external application to the skin | SHISEIDO COMPANY, LTD. (JP) | 2011-08-23 | — | — | US | disclosed |
| US-8003083-B2 | Benzylidene malonamide and salt thereof, ultraviolet ray absorbent, and agent for external application to the skin | SHISEIDO COMPANY, LTD. (JP) | 2011-08-23 | — | — | US | disclosed |
| US-20100254921-A1 | Benzylidene Malonamide And Salt Thereof, Ultraviolet Ray Absorbent, And Agent For External Application To The Skin | SHISEIDO COMPANY, LTD. (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100254921-A1 | Benzylidene Malonamide And Salt Thereof, Ultraviolet Ray Absorbent, And Agent For External Application To The Skin | SHISEIDO COMPANY, LTD. (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2030966-A1 | BENZYLIDENE MALONAMIDE AND SALT THEREOF, ULTRAVIOLET RAY ABSORBENT, AND AGENT FOR EXTERNAL APPLICATION TO THE SKIN | SHISEIDO COMPANY, LTD. (JP) | 2009-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100254921-A1 | Benzylidene Malonamide And Salt Thereof, Ultraviolet Ray Absorbent, And Agent For External Application To The Skin | UROD, MAL2, SI | TSHR 3621/4885MAPK1 959/4885MEN1 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.