Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8386481 | 0.96 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2ACYP26A1 | |
| SCHEMBL17961915 | 0.92 | ALDH1A1 (0.56) | NPC1RAB9AMEN1KMT2ACYP26A1 | |
| SCHEMBL11961891 | 0.92 | ALDH1A1 (0.56) | NPC1RAB9AMEN1KMT2ACYP26A1 | |
| SCHEMBL379238 | 0.89 | RAPGEF4 (0.63) | NPC1RAB9AMEN1KMT2ACYP26A1 | |
| SCHEMBL25912039 | 0.85 | RAPGEF4 (0.58) | NPC1RAB9AMEN1KMT2ACYP26A1 | |
| SCHEMBL1673420 | 0.82 | RAPGEF4 (0.67) | NPC1RAB9AMEN1KMT2ACYP26A1 | |
| SCHEMBL15152202 | 0.82 | RAPGEF4 (0.53) | NPC1RAB9AMEN1KMT2ACYP26A1 | |
| SCHEMBL3499238 | 0.81 | MEN1 (0.63) | NPC1RAB9AMEN1KMT2ACYP26A1 | |
| SCHEMBL8810023 | 0.81 | CYP26A1 (0.53) | NPC1RAB9AMEN1KMT2ACYP26A1 | |
| SCHEMBL18583900 | 0.80 | RAPGEF4 (0.52) | NPC1RAB9AMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003583-B2 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-7501386-B2 | Lubricants for automotive and truck crankcase lubricants; as well as transmission lubricants, gear lubricants, hydraulic fluids, compressor oils, diesel and marine lubricants; superior oxidation inhibition; Phenyl-(1,2,3,4-tetrahydro-quinolin-6-yl)-amine, diphenylamine | CHEVRON ORONITE COMPANY, LLC (US) | 2009-03-10 | — | — | US | disclosed |
| US-20070142243-A1 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
| US-20070142246-A1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142246-A1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | AHR, ARNT, HRH2 | NPC1 1276/4885RAB9A 4440/4885MEN1 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.