SCHEMBL1237755

SCHEMBL1237755

[CH2]c1cccc(S(=O)(=O)O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
HSD17B10 Q99714 4/20 0.57
TSHR P16473 3/20 0.57
TDP1 Q9NUW8 3/20 0.57
SMN1; SMN2 Q16637 1/20 0.52
NAPRT Q6XQN6 1/20 0.42
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
LMNA P02545 1/20 0.39
NT5E P21589 1/20 0.38
SNCA P37840 1/20 0.38
SENP3 Q9H4L4 2/20 0.37
SENP2 Q9HC62 2/20 0.37
SENP1 Q9P0U3 2/20 0.37
SUMO2 P61956 1/20 0.37
SUMO1 P63165 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
CASP6 P55212 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1563586 0.83 ALDH1A1 (0.70) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL151444 0.83 ALDH1A1 (0.70) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL2289285 0.80 ALDH1A1 (0.67) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
Hydrochloric Acid SCHEMBL5873323 0.80 ALDH1A1 (0.67) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL2785772 0.80 ALDH1A1 (0.67) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
Hydrochloric Acid SCHEMBL890392 0.80 ALDH1A1 (0.67) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL128236 0.80 ALDH1A1 (0.67) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL5343773 0.80 ALDH1A1 (0.67) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL9550121 0.80 ALDH1A1 (0.67) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2
SCHEMBL29222010 0.80 ALDH1A1 (0.67) ALDH1A1HSD17B10TSHRTDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1020178-B1 Dental bleaching system and method ADDENT INC (US) 2003-10-01 EP claimed
WO-2000030632-A1 ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS EISAI CO., LTD. (JP) 2000-06-02 WO claimed
US-5811081-A Use of hydroxybenzotriazoles for enhancing the sun protection factor of cellulosic fibre materials CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-22 US claimed
US-5534395-A Method of processing silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1996-07-09 US claimed
EP-0708197-A2 Utilisation of hydroxybenztriazoles for increasing the sun-ray filter index of fibrous cellulosic materials CIBA-GEIGY AG (CH) 1996-04-24 EP claimed
US-4180503-A FOR DYEING POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-12-25 US claimed
US-10808059-B2 Polymer CANON KABUSHIKI KAISHA (JP) 2020-10-20 US disclosed
US-10358567-B2 Compound, ink, ink cartridge and ink jet recording method CANON KABUSHIKI KAISHA (JP) 2019-07-23 US disclosed
US-20180355086-A1 POLYMER CANON KABUSHIKI KAISHA (JP) 2018-12-13 US disclosed
US-20170247557-A1 COMPOUND, INK, INK CARTRIDGE AND INK JET RECORDING METHOD CANON KABUSHIKI KAISHA (JP) 2017-08-31 US disclosed
US-8399481-B2 Compounds XENTION LTD (GB) 2013-03-19 US disclosed
US-7985266-B2 Keratin dyeing compositions comprising a radical scavenger and a chelant and use thereof THE PROCTER & GAMBLE COMPANY (US) 2011-07-26 US disclosed
US-20110035886-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof NOXELL CORPORATION 2011-02-17 US disclosed
US-5061794-A Effective against pseudomonads BANYU PHARMACEUTICAL CO., LTD. (JP) 1991-10-29 US disclosed
EP-0432499-A1 Method for processing silver halide photographic material and composition having fixing ability FUJI PHOTO FILM CO., LTD. (JP) 1991-06-19 EP disclosed
EP-0397190-A1 Azoic pigments, their production and their use SYNTHESIA akciová spolecnost (CZ) 1990-11-14 EP disclosed
EP-0241901-A2 Cephalosporin derivatives, processes for their preparation and antibacterial agents Banyu Pharmaceutical Co., Ltd. (JP) 1987-10-21 EP disclosed
US-4268622-A Photographic light-sensitive materials having dyed layers FUJI PHOTO FILM CO., LTD. (JP) 1981-05-19 US disclosed
EP-0014031-A1 Water-soluble monoazo dyes of the azobenzene series, their preparation and process for the colouration of polyamide textile materials IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-08-06 EP disclosed
US-4180503-A FOR DYEING POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10358567-B2 Compound, ink, ink cartridge and ink jet recording method JAK1, JAK2, ETV6 ALDH1A1 176/4885HSD17B10 3367/4885TSHR 3684/4885
US-20170247557-A1 COMPOUND, INK, INK CARTRIDGE AND INK JET RECORDING METHOD JAK1, JAK2, ETV6 ALDH1A1 176/4885HSD17B10 3367/4885TSHR 3684/4885
US-20110035886-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and a Chelant and Use Thereof KRT18, LPO, KRTCAP2 ALDH1A1 354/4885HSD17B10 1578/4885TSHR 4386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.