Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377636 | 0.91 | ALDH1A1 (0.41) | LMNARELAALDH1A1KDM4ECYP1A2 | |
| SCHEMBL12377601 | 0.87 | MAOB (0.44) | LMNARELAALDH1A1CA1MGLL | |
| SCHEMBL17486894 | 0.82 | MAOB (0.48) | LMNARELAALDH1A1KMT2AMAPT | |
| SCHEMBL9972129 | 0.82 | MAOB (0.48) | LMNARELAALDH1A1KMT2AMAPT | |
| SCHEMBL17486895 | 0.81 | MAOB (0.47) | LMNARELAALDH1A1KMT2AMAPT | |
| SCHEMBL16807032 | 0.81 | MAOB (0.47) | LMNARELAALDH1A1KMT2AMAPT | |
| SCHEMBL13609992 | 0.80 | ALDH1A1 (0.46) | RELAALDH1A1HPGDCA1KMT2A | |
| SCHEMBL17486890 | 0.80 | ALDH1A1 (0.46) | RELAALDH1A1HPGDCA1KMT2A | |
| SCHEMBL16807030 | 0.80 | TRPM8 (0.42) | LMNARELAALDH1A1KDM4ECYP2C9 | |
| SCHEMBL12377600 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003287-B2 | Low temperature charge transportability and potential, sensitivity and photoresponsiveness; durability | SHARP KABUSHIKI KAISHA (JP) | 2011-08-23 | — | — | US | disclosed |
| US-20080166642-A1 | Electrophotographic photoconductor and image-forming apparatus | SHARP KABUSHIKI KAISHA (JP) | 2008-07-10 | — | — | US | disclosed |