Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377599 | 0.91 | LMNA (0.36) | ALDH1A1HPGDMAPTGAAMEN1 | |
| SCHEMBL13609992 | 0.90 | ALDH1A1 (0.46) | ALDH1A1HPGDCYP3A4MAPTGAA | |
| SCHEMBL17486890 | 0.90 | ALDH1A1 (0.46) | ALDH1A1HPGDCYP3A4MAPTGAA | |
| SCHEMBL16807030 | 0.90 | TRPM8 (0.42) | ALDH1A1HPGDCYP3A4MAPTGAA | |
| SCHEMBL17486892 | 0.86 | CYP1B1 (0.45) | ALDH1A1HPGDCYP3A4MAPTGAA | |
| SCHEMBL13986161 | 0.84 | NFE2L2 (0.45) | ALDH1A1HPGDCYP3A4MAPTTRPM8 | |
| SCHEMBL13242001 | 0.83 | MAPT (0.45) | ALDH1A1HPGDCYP3A4MAPTTRPM8 | |
| SCHEMBL13622305 | 0.83 | MAPT (0.43) | ALDH1A1HPGDCYP3A4MAPTGAA | |
| SCHEMBL4367692 | 0.83 | CES2 (0.44) | ALDH1A1HPGDCYP3A4MAPTMEN1 | |
| SCHEMBL20109429 | 0.82 | TRPM8 (0.44) | ALDH1A1HPGDCYP3A4MAPTTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003287-B2 | Low temperature charge transportability and potential, sensitivity and photoresponsiveness; durability | SHARP KABUSHIKI KAISHA (JP) | 2011-08-23 | — | — | US | disclosed |