Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12415468 | 0.85 | KDM4E (0.56) | ALDH1A1HSD17B10HPGDALOX15MAPK1 | |
| SCHEMBL2291662 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL1712335 | 0.80 | MTNR1B (0.42) | ALDH1A1HSD17B10MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL12377718 | 0.79 | KDM4E (0.44) | ALDH1A1HSD17B10HPGDALOX15MAPK1 | |
| SCHEMBL10809062 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ESMN1; SMN2NQO2 | |
| SCHEMBL1554320 | 0.77 | KDM4E (0.53) | ALDH1A1HSD17B10HPGDMAPTKDM4E | |
| SCHEMBL28785628 | 0.76 | KDM4E (0.57) | ALDH1A1HSD17B10HPGDALOX15MAPK1 | |
| SCHEMBL28495794 | 0.76 | NQO2 (0.57) | ALDH1A1HSD17B10HPGDALOX15MAPK1 | |
| SCHEMBL3414003 | 0.76 | NQO2 (0.50) | ALDH1A1MAPK1MAPTKDM4ENQO2 | |
| SCHEMBL24822355 | 0.75 | HDAC6 (0.49) | ALDH1A1HSD17B10HPGDMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8535511-B2 | Methods for electrochemical analysis using matrix compositions with alkylphenazine quaternary salt and a nitrosoaniline | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-8535511-B2 | Methods for electrochemical analysis using matrix compositions with alkylphenazine quaternary salt and a nitrosoaniline | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-8008037-B2 | Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20090246808-A1 | BIOSENSOR WITH IMPROVED ANALYTE SPECIFICITY | ROCHE DIABETES CARE, INC. | 2009-10-01 | — | — | US | disclosed |