Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.36 |
| ▸ | FURIN | P09958 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13202008 | 0.87 | SLC6A5 (0.38) | SLC6A5FURINCA1CA2CYP1A2 | |
| SCHEMBL13949815 | 0.79 | SLC6A5 (0.41) | SLC6A5CA1CA2CYP1A2TSHR | |
| SCHEMBL13202342 | 0.79 | SLC6A5 (0.38) | SLC6A5CA1CA2CYP1A2TSHR | |
| SCHEMBL2290844 | 0.78 | SLC6A5 (0.37) | SLC6A5CA1CA2CYP1A2TSHR | |
| SCHEMBL10557329 | 0.75 | TSHR (0.41) | SLC6A5CA1CA2CYP1A2TSHR | |
| SCHEMBL14943105 | 0.70 | — | — | |
| SCHEMBL7444824 | 0.70 | — | — | |
| SCHEMBL23452547 | 0.68 | FAAH (0.59) | KMT2AFAAH | |
| SCHEMBL8508766 | 0.68 | SLC6A5 (0.49) | SLC6A5LMNATHRBBLMKMT2A | |
| SCHEMBL11142780 | 0.68 | CA1 (0.47) | SLC6A5CA1CA2CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008007-B2 | S-adenosyl-L-methionine analogs with extended activated groups for transfer by methyltransferases | RWTH AACHEN (DE) | 2011-08-30 | — | — | US | disclosed |