Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12378930 | 0.87 | SLC6A5 (0.36) | SLC6A5CYP1A2TSHRGABRR3GABRP | |
| SCHEMBL13202342 | 0.84 | SLC6A5 (0.38) | SLC6A5CYP1A2TSHRGABRR3GABRP | |
| SCHEMBL13949815 | 0.84 | SLC6A5 (0.41) | SLC6A5CYP1A2TSHRGABRR3GABRP | |
| SCHEMBL2290844 | 0.82 | SLC6A5 (0.37) | SLC6A5CYP1A2TSHRGABRR3GABRP | |
| SCHEMBL23452547 | 0.80 | FAAH (0.59) | KMT2AFAAH | |
| SCHEMBL10557329 | 0.79 | TSHR (0.41) | SLC6A5CYP1A2TSHRGABRR3GABRP | |
| SCHEMBL11930640 | 0.79 | — | — | |
| SCHEMBL27394937 | 0.77 | CASP2 (0.47) | HDAC3LMNAHDAC1HDAC2HDAC8 | |
| SCHEMBL16675567 | 0.75 | PHF8 (0.45) | LMNA | |
| SCHEMBL85468 | 0.74 | KDM4E (0.55) | SLC6A5HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874790-B1 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2010-08-18 | — | — | EP | disclosed |