SCHEMBL12379364

SCHEMBL12379364

C=C(C)C(=O)OCCNC(=O)c1ccc(C(C)CC)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KMT2A Q03164 4/20 0.41
MEN1 O00255 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALDH1A1 P00352 3/20 0.41
IARS1 P41252 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HTT P42858 2/20 0.41
HPGD P15428 3/20 0.40
OPRK1 P41145 1/20 0.40
NPC1 O15118 2/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TP53 P04637 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10049583 0.83 KMT2A (0.50) TSHRKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL14565939 0.83 SMN1; SMN2 (0.49) TSHRKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL25784266 0.82 ALDH1A1 (0.41) TSHRL3MBTL1KMT2AMEN1ALDH1A1
SCHEMBL10093635 0.82 KMT2A (0.44) TSHRL3MBTL1KMT2AMEN1ALDH1A1
SCHEMBL25784268 0.82 THRB (0.44) TSHRKMT2AMEN1CYP1A2CYP3A4
SCHEMBL21246818 0.80 NPC1 (0.56) TSHRL3MBTL1KMT2AMEN1CYP1A2
SCHEMBL16693227 0.80 LMNA (0.50) TSHRKMT2AMEN1CYP1A2CYP3A4
SCHEMBL23422510 0.80 TDP1 (0.47) TSHRL3MBTL1KMT2AMEN1ALDH1A1
SCHEMBL16693290 0.79 HDAC3 (0.49) KMT2AMEN1CYP1A2CYP3A4ALDH1A1
SCHEMBL24951994 0.79 NPC1 (0.40) TSHRL3MBTL1KMT2AMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217718-A1 METHOD FOR PRODUCING LIGHT-EMITTING ELEMENTS CENTRAL GLASS COMPANY, LIMITED (JP) 2023-07-06 US disclosed
US-20150000544-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD THEREOF FUJIFILM CORPORATION (JP) 2015-01-01 US disclosed
US-20130216950-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2013-08-22 US disclosed
US-7998652-B2 capable of giving a large number of sheets of good printed matter using a lithographic printing plate prepared with a practical amount of energy FUJIFILM CORPORATION (JP) 2011-08-16 US disclosed
US-20110168044-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-07-14 US disclosed
US-7713681-B2 Method for preparation of lithographic printing plate FUJIFILM CORPORATION (JP) 2010-05-11 US disclosed
US-7700265-B2 Image forming method, planographic printing plate precursor, and planographic printing method FUJIFILM CORPORATION (JP) 2010-04-20 US disclosed
US-20100062375-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-03-11 US disclosed
US-20100003618-A1 POLYMER HAVING POLYMERIZABLE GROUP, POLYMERIZABLE COMPOSITION, PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND PLANOGRAPHIC PRINTING METHOD USING THE SAME KUNITA KAZUTO 2010-01-07 US disclosed
US-7618762-B2 Polymer having polymerizable group, polymerizable composition, planographic printing plate precursor, and planographic printing method using the same FUJIFILM CORPORATION (JP) 2009-11-17 US disclosed
US-20090246702-A1 METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20080182205-A1 Polymer having polymerizable group, polymerizable composition, planographic printing plate precursor, and planographic printing method using the same KUNITA KAZUTO 2008-07-31 US disclosed
US-20080160451-A1 METHOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20070224535-A1 Image Forming Method, Planographic Printing Plate Precursor, and Planographic Printing Method FUJIFILM CORPORATION (JP) 2007-09-27 US disclosed